Besides better aeration and mixing properties, what other advantages do stirred tank bioreactors have over shake flasks ?

Stirred tank bioreactors provide advantage over shake flasks . besides aeration and mixing properties Stirred tank bioreactors are useful in a number of ways

(i) They provide optimum growth conditions (temperature, pH, substrate, salts, vitamins, oxygen) to achieve the desired product.

(ii) They are cost effective .

(iii) Due to baffles, oxygen transfer rate is very high

(iv) Capacity of stirred tank is more as compared to shake flasks.