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Reproduction In Organisms

Question
CBSEENBI12003440
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Assertion : Only a boy child could be born with a substitution of glutamic acid by valine on 6 codon of beta-chain of haemoglobin.

Reason : The gene for the above mutation is found on Y-chromosome.

  • If both assertion and reason are true and reason is the correct explanation of assertion.

  • If both assertion and reason are hue but reason is not the correct explanation of assertion.

  • If assertion is true but reason is false.

  • If both assertion and reason are false.

Solution

D.

If both assertion and reason are false.

Sickle cell anaemia is an autosomal recessive hereditary disorder in which the erythrocytes become sickle-shaped under oxygen deficiency as during strenuous exercise and at high altitudes. The disease is caused by the formation of an abnormal haemoglobin called haemoglobin- S. It differs from normal haemoglobin in only one amino acid- 6th amino acid of β- chain. Glutamic acid is replaced by valine due to substitution of T by A in the second position of the triplet codon (CTC) which is changed to CAC in the β- haemoglobin gene on chromosome 11.

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