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Biomolecules

Question
CBSEENCH12009643

Explain the following:
Glucose responds Fehling solution and osazone, it does not react with Schiff’s base and sodium bisulphite.

Solution
Fehling and osazone reactions are irreversible and hence the equilibrium is shifted to restore the low concentration (0.02%) of open chain aldehydic form with the result glucose reacts with these reagents. On the other hand the Schiff and bisulphite reactions are reversible and hence the equilibrium of such reactions favours unreacted hemiacetal.