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Chemical Coordination and Integration
Question
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When thyroxine has negative feed back effect ?

Answer

When amount of thyroxine in plasma increases than normal, then thyroxine exerts inhibiting effect on hypothalamus for non secretion of TSH (Thyroid stimulating hormone). Thus, secretion of thyroxin stops due to non secretion of TSH by the anterior lobe of pituitary gland. Thus, it is called negative feed back.

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