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Chemical Coordination and Integration
Question
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Which of the following pairs of hormones can easily pass through the cell membrane and binds to a receptor inside it (mostly in the nucleus)

  • Insulin, glucagon

  • Thyroxine, insulin

  • Somatostatin, oxytocin

  • Cortisol, testosterone

Answer

D.

Cortisol, testosterone

Cortisol and testosterone are steroidal in nature. Steroid hormones are lipid soluble and easily pass through cell membrane of a target cell into the cytoplasm. In the cytoplasm they bind to specific intracellular receptors (proteins) to form a hormone receptor complex that enters the nucleus.

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