Spindle fibre is made up of

• tubulin

• humulin

• intermediate filament

• flagelin

A.

tubulin

Tubulin is a cytoskeletal globular protein that polymerizes to form microtubules. These radiate from each end of the cell to form a basket like arrangement which helps in the movement of chromosomes to poles. Microtubules also play an important role in the movement of cilia and flagella.

Intermediate filaments are tough rope- like bundles or protein (keratin, desmin, peripherin, vimentin). They provide mechanical stability to cells and interact with microfilaments and microtubules to form cytoskeleton.