The chemiosmotic coupling hypothesis of oxidative phosphorylation proposes that Adenosine Triphosphate (ATP) is formed because
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High energy bonds are formed in mitochondrial proteins
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ADP is pumped out of the matrix into the intermembrane space
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a proton gradient forms across the inner membrane
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there is a change in the permeability of the inner mitochondrial membrane toward Adenosine Diphosphate (ADP)
