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Molecular Basis Of Inheritance

Question
CBSEENBI12002693

What is antissense technology? 

  • A cell displaying a foreign antigen used for synthesis of antigens

  • Production of somaclonal variants in tissue cultures. 

  • When a piece of RNA that is complementary to sequence is used to stop expression of a specific gene.

  • all mutations, whether dominant or recessive are expressed in haploids

Solution

C.

When a piece of RNA that is complementary to sequence is used to stop expression of a specific gene.

The antisense RNA technology simply involves the synthesis of RNA molecules that are complementary to the mRNA molecules produced by transcription of a given gene.  Usually t his antisense RNA will not contain the regulatory sequences required for translation but even if does it will not usually specify a functional product. Instead, most antisense RNAs contain multiple termination codons in all three reading frames. However, when antisense RNA molecules are present in the same cytosol with sense (mRNA) molecules of a gene, the antisense RNA and mRNA molecules will anneal to form duplex RNA molecules. These duplex RNA molecules cannot be translated thus, the presence of antisense RNA will block translation of the mRNA of the affected gene.