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Principles Of Inheritance And Variation

Question
CBSEENBI12002228

If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?

  • No Chance

  • 50%

  • 25%

  • 100%

Solution

C.

25%

Thalassemia is the disorder due to reduced synthesis of either the alpha or beta chains, likewise designated as alpha or beta - thalassemias. When this autosomal mutant gene is present in a double dose. The disease is severely called as thalassemia major.