Sponsor Area

Human Reproduction

Question
CBSEENBI12002124

Expand VNTR and describe its role in DNA fingerprinting.

Solution

VNTR stands for “Variable Number of Tandem Repeats”.
The VNTR belongs to a class of satellite DNA referred to as mini-satellite. A small DNA sequence is arranged tandemly in many copy numbers. The copy number varies from chromosome to chromosome in an individual. The numbers of repeat show very high degree of polymorphism. As a result th size of VNTR varies in size from 0.1 to 20 kb. Consequently, after hybridization with VNTR probe, the autoradiogram gives many bands of differing sizes. These bands give characteristic pattern for an individual DNA which is used to identify individuals.