Both Haemophilia and Thalassemia are blood related disorders in humans. Write their causes and the difference between the two. Name the category of genetic disorder they both come under.

Solution

Both are Mendelian disorders.
* Haemophilia is a sex linked recessive disorder. The gene for haemophilia is located on X-chromosome. The gene passes from a carrier female to her son.
* Thalessemia is an autosomal linked recessive disease.
* It occurs due to either mutation or deletion resulting in reduced rate of synthesis of one of globin chains of haemoglobin.
* The difference between Haemophilia and Thalessemia is : - In haemophilia, clotting is affected, i.e. there can be a non-stop bleeding even after a minor cut.
* In Thalessemia, anaemia is the characteristic of this disease

Some More Questions From Principles of Inheritance and Variation Chapter

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Principles Of Inheritance And Variation

Both Haemophilia and Thalassemia are blood related disorders in humans. Write their causes and the difference between the two. Name the category of genetic disorder they both come under.

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