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Molecular Basis Of Inheritance

Question
CBSEENBI12001991
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A. Name the enzyme that catalyses the transcription of hnRNA.

B. Why does the hnRNA need to undergo changes ? List the changes hnRNA undergoes and where in the cell such changes take place.

Solution

A. hnRNA is designated as heterogeneous nuclear RNA. Transcription of hnRNA is catalyses by – RNA polymerase II.
B. During primary transcription formation the mRNA contains both coding and non-coding regions called as exons and introns. The sequence is then subjected to splicing (process of removal of introns form primary transcript).
hnRNA then undergo capping and tailing.
Capping is a process where addition of methyl guanosine triphosphate takes place at 5' end of hnRNA, while tailing is done by the addition 200- 300 adenylate residues at 3' end. The final mRNA is then transported outside of nucleus by nuclear pore to the cytoplasm for translation.

Some More Questions From Molecular Basis of Inheritance Chapter

List the function of RNA.

List the number of base pairs in :

(i) lambda bacteriophage

(ii) E.coli and

(iii) haploid content of human DNA.

Comment two chains of DNA have antiparallel polarity.

What is the difference between DNAs and DNAase ?

Which was first genetic material ?

Suggest one evidence to prove that RNA was first genetic material.

Why was RNA unstable ?

What made DNA more preferrable as genetic material ?

Process of replication is completed in how much time in E.coli ?

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