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Molecular Basis Of Inheritance

Question
CBSEENBI12001966
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(a) How are the following formed and involved in DNA packaging in a nucleus of a cell?

(b) Differentiate between Euchromatin and Heterochromatin

Solution

i. Histone octomer - The histones are positively charged, basic proteins called histones. Histones are rich in basic amino acids like lysines and arginines. Histones are organised to form a unit of eight molecules called an histone octamer.

ii. Nucleosome - The negatively charged DNA is wrapped around the positively charged histone octamer to form the structure called nucleosome. A typical nucleosome contains 200 bp of DNa helix.

iii. Chromatin - The nucleosome are the repeating units and together form chromatin. The nucleosome appear like beads on strings on the chromatin.

The chromatin is packaged to form chromatin fibres that further coil and condense at metaphasic stage of cell division to form chromosome. This involves non-histone proteins for packaging called the No-histone Chromosomal (NHC) proteins.

(b)  

Euchromatin Heterochromatin
Region of the chromatin which is loosely packed. Region of the chromatin which is densely packed
Stains light Stains dark.

Some More Questions From Molecular Basis of Inheritance Chapter

Which was first genetic material ?

Suggest one evidence to prove that RNA was first genetic material.

Why was RNA unstable ?

What made DNA more preferrable as genetic material ?

Process of replication is completed in how much time in E.coli ?

What is average rate of polymerization ?

List three components of transcription unit.

Which RNA acts as an adapter ?

Name three kinds of polymerases.

What is splicing ?

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