Question
(a) Mention the cause and the body system affected by ADA deficiency in humans.
(b) Name the vector used for transferring ADA-DNA into the recipient cells in humans. Name the recipient cells.Solution
(a) ADA (Adenosine deaminase) is an enzyme crucial for immune system. Its deficiency is caused due to the deletion of the gene coding for adenosine deaminase. Immune system is affected by ADA deficiency in humans.
(b) Retrovirus is used as a vector to introduce functional ADA cDNA into the lymphocytes cells (recipient cells).
