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Human Reproduction

Question
CBSEENBI12001866

(a) Where does fertilization occur in human ? Explain the events that occur during this process.

(b) A couple where both husband and wife are producing functional gametes, but the wife is still unable to conceive, is seeking medical aid. Describe any one method that you can suggest to this couple to become happy parents.

Solution

(a) Fertilization occur in the fallopian tube of females in human.
The events that occur during this process are :

i. The sperms come in contact with zona pellucida  of the ovum.
ii. The sperm induces change in the membrane. 
iii. Blocks entry of other sperms / ensures only one sperm fertilizes the ovum / prevents polyspermy. 
iv. The secretion of acrosome helps the sperm to enter the cytoplasm of the ovum by degrading the wall of the ova. 
v. Entry of sperm induces completion of second meiotic division forming ovum and 2nd polar body 
vi. The haploid nucleus of Sperm and that of ovum fuses. 
vii. Fertilisation completes on the formation of diploid Zygote.
b. Method suggested for the couple :

In vitro fertilisation followed by embryo transfer (ET)
In this method, popularly known as test tube baby programme, ova from the wife/donor (female) and sperms from the husband/donor (male) are collected and are induced to form zygote under simulated conditions in the laboratory