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Molecular Basis Of Inheritance

Question
CBSEENBI12001792

The base sequence in one of the strands of DNA is TAGCATGAT.

(i) Give the base sequence of its complementary strand.

(ii) How are these base pairs held together in a DNA molecule?

(iii) Explain the base complementarity rules. Name the scientist who framed this rule.

Solution

(i) The base sequence of the complementary strand will be - ATCGTACTA.

(ii) The base pairs in the DNA molecules are held together by hydrogen bonds. There are two hydrogen bonds between adenine and thymine and three hydrogen bonds between guanine and cytosine.

(iii) Base Complementarity Rule: A purine always pairs with a pyrimidine in a DNA molecule i.e. 

A will pair with T and G will pair with C.

The ratio of A and T or C and G will always be 1.

Erwin Chargaff framed the base complementarity rule.