A child by the family from Thalassemia is born to a normal couple. But the mother is being blamed by the family for delivering a sick baby. (a) What is Thalassemia?

(b) How would you counsel the family not to blame the mother for delivering a child suffering from this disease? Explain.
(c) List the values your counseling can propagate in the families.

Solution

(a) Thalassemia - is an autosomal recessive blood disease which can occur due to deletion of the genes controlling the formation of globin chains (commonly Alpha and Beta) of haemoglobin.

(b) Mother cannot be blamed for the disease as, it is an autosomal recessive blood disorder. The genes for the synthesis of globin chains are present on autosomes.

(i) Formation of Alpha chain is controlled by 2 genes present on chromosome 16 and

(ii) Formation of Beta-chain is controlled by one gene present on chromosome 11manifestation of the disease occurs when the progeny receives defective genes from both the parents (as thalassemia is expressed is homozygous recessive condition only).

(i) One should be aware of such autosomal diseases and should get themselves checked for the same before marriage.

(ii) Manifestation of the disease occurs due to defective genetic set up of both the parent (so it is not only that the mother should be blamed.

Some More Questions From Principles of Inheritance and Variation Chapter

For Daily Free Study Material Join wiredfaculty

Principles Of Inheritance And Variation

Some More Questions From Principles of Inheritance and Variation Chapter

Write the genotypes of man with blood group A.

What is Mendel’s monohybrid phenotypic ratio ?

Write down Mendel’s dihybrid Phenotypic ratio

Who were the rediscoverers of Mendelism ?

What are the real determinants of what an organism will become ?

What is the unique feature of F1 generation ?

What will be the genetic make up of an organism which suffers from sickle cell anaemia ?

What do the symbols square and circle in a pedigree chart indicate ?

Define heterogamy. Give an example.

How many chromosomes are found in human cells ?

Mock Test Series

NCERT Sample Papers

Entrance Exams Preparation

Phone Number

Email Address

Location