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Molecular Basis Of Inheritance

Question
CBSEENBI12000352

How is long DNA molecule adjusted in a nucleus.

Solution

The Long DNA molecule is adjusted in the nucleus in the following way-:
The negatively charged DNA is wrapped around the positively charged histone octamer. The structure formed is called nucleosome that contains 200bp of DNA helix.
The nucleosomes repeating units form chromatin in the nucleus. Nucleosomes look like bead on string in chromatin.
The chromatin (bead on string structure) are packed to  form the chromatin fibres that coil further to give metaphase chromosomes.

Nucleosome