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Question

What is point mutation? Give one example.

Prabhat Rajore · Accepted Answer

Point mutation is the mutation or alteration in a single base pair of the DNA sequence. For example Sickle-cell anaemia in humans . In Sickle-cell anemia only a single base pair is altered which forms Valine instead of Glutamine at 6^th position in the haemoglobin polypetide.

HbA peptide represents the normal peptide whereas the HbS represents the altered peptide.

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Principles Of Inheritance And Variation

What is point mutation? Give one example.

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