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Principles Of Inheritance And Variation

Question
CBSEENBI12003123

The trisomy for 21st chromosome is called

  • Down's syndrome

  • Turner's syndrome

  • Sickle cell anaemia

  • Klinfelter's syndrome

Solution

A.

Down's syndrome

Abnormality Cause Characteristic
Down's Syndrome Trisomy of 21st chromosome (45 A + XX/ XY) Mental retardation, prominent head, flattened nasal bridge, open mouth, short stature etc
Turner's Syndrome Non- disjunction of sex chromosome (2n = 45; 44A +XO) Sterile female, webbed neck, no breast development, no menstruation or egg production
Klinefelter's Syndrome Non- disjunction of sex chromosomes (2n = 47; 44A + XXY) Sterile male with low IQ, testes underdeveloped.
Sickle cell anaemia Molecular gene mutation of gene HbA Sickle shaped RBCs, do not transport O2 efficiently