The main reason why antibiotics could not solve all the problems of bacteria mediated diseases is

insensitivity of the individual following prolonged exposure to antibiotics

inactivation of antibiotics by bacterial enzymes

decreased efficiency of the immune system

the development of mutant strains resistant to antibiotics.

Solution

the development of mutant strains resistant to antibiotics.

A major problem in the treatment of bacterial mediated diseases is that many bacteria have been found to show resistance to antibiotics. The emergence of antibiotic-resistant bacteria is closely linked to the extent that antibiotics are used in humans and items of human diet. Resistant strains may appear rapidly or slowly, according to the amount or type of antibiotic used. Bacteria occur in such large numbers that there is a high chance of a mutant individual eventually appearing in the population. As soon as it does, use of the antibiotic to which it is resistant will give it a selective advantage over non-resistant types and it will multiply and eventually become the dominant type.

Antibiotics may also be destroyed by enzymes inside the cells being targetted. A well-known and important example is the group of enzymes known as penicillinases which hydrolyses and destroys penicillins and cephalosporins.

Some More Questions From Human Health and Disease Chapter

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Human Health And Disease

Some More Questions From Human Health and Disease Chapter

What is the significance of ‘Typhoid Mary’ ?

Name the most infectious human common ailment and write its causative agent.

Out of four species of malaria which is most serious ?

Name the vector of malaria.

Write the causative agent of (i) amoebiasis and (ii) ascariasis.

Name the disease caused by Wuchereria bancrofti.

List three fungal genera which cause ringworm.

List two symptoms of ring worm.

Name the two wide spread diseases caused by Aedes mosquitoes.

Name the primary lymphoid organs.

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