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Principles Of Inheritance And Variation

Question
CBSEENBI12047507

A women with albinic father marries an albinic man. The proportion of her progeny is

  • 2 normal : 1 albinic

  • All normal

  • All albinic

  • 1 normal : 1 albinic

Solution

D.

1 normal : 1 albinic

Albinism is an autosomal recessive metabolic disorder. It is characterised by the complete or partial absence of pigment in the skin, hair and eyes due to the absence or defect of tyrosinase, a copper-containing enzyme involved in the production of melanin.

An albino man (rr) marries a normal women (RR). Their progeny carries one recessive allele (r) and one dominant allele (R), i.e. it is heterozygous. When this heterozygous daugther (Rr) marries albinic man (rr), the proportion of her progeny found out to be 1 albino and 1 normal.