Sponsor Area

Human Health And Disease

Question
CBSEENBI12047433

Which one of the following combinations acts as a usual antigen binding site of an antibody?

  • Variable regions of a light and another heavy chain

  • Variable regions of two light chains

  • Variable regions of two heavy chains

  • Variable region of a heavy chain and constant region of a light chain

Solution

A.

Variable regions of a light and another heavy chain

Each antibody molecule has four peptide chains, two small called light chains and two longer called heavy chains. Antigen-binding site (paratope) in an antibody includes variable regions of both heavy and light chains.