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Microbes In Human Welfare

Question
CBSEENBI12047420
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Which one of the following antibiotics kills bacterial cells by inhibiting the polymerisation of peptidoglycan?

  • Aminoglycosides

  • Fluoroquinolones

  • Quinines

  • Penicillins

Solution

D.

Penicillins

Some antibacterial drugs such as periicillin interfere with the production of peptidoglycan by binding to bacterial enzymes known as penicillin-binding proteins or transpeptidases. For a bacterial cell to reproduce, more than a million peptidoglycan subunits must be attached to existing subunits. Transpeptides form the bonds between oligopeptide crosslinks in peptidoglycan-penicillin inhibit this binding and kills bacterial cells.

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