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Molecular Basis Of Inheritance

Question
CBSEENBI12047388
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If the sequence of bases in the coding strand of a double-stranded DNA is 5'-GTTCGAGTC-3', the sequence of bases in its transcript will be

  • 5'-GACUCGAAC-3'

  • 5'-CAAGCUCAG-3'

  • 5'-GUUCGAGUC-3'

  • 5'-CUGAGCUUG-3'

Solution

C.

5'-GUUCGAGUC-3'

DNA is made up of two polynucleotide chains having antiparallel polarity. Therefore, when one chain has 5' → 3' polarity the other chain will have 3' → 5' polarity. Thus, if the sequence of the bases in the coding strand of a double- stranded DNA is 5' GTTCGAGTC-3' its complementary strand will have 3'-CAAGCTCAG-5'.

In case of transcript, i.e., mRNA, the sequence will be 5'-GUUCGUGUC-3' (Uracil is present instead of thymine).

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