Sponsor Area

Human Health And Disease

Question
CBSEENBI12047194

Which lg is produced in primary immune response

  • IgA

  • IgG

  • IgE

  • IgM

Solution

D.

IgM

IgM antibodies constitute the major component of the natural antibodies and is also the first class of antibodies produced during a primary antibody response. The IgM-type antibodies differ from other classes of antibodies in that they are predominantly produced by B1 cells, in the absence of apparent stimulation by specific antigens. In addition, IgM antibodies are mostly encoded by germline V gene segments and have low affinities but broad specificites to both foreign and self structures.