Which among the following statements is correct with respect to functional structure of glomerular membrane?
I. The endothelium is perforated by small holes called fenestral.
II. The basement membrane is present inside the endothelium and is composed of meshwork of collagen.
III. The epithelium of visceral layer has cells, which are of peculiar shape and are called podocytes.
IV. The shapes between pedicels are called slit pores through which glomerular filterate filters.
Choose the correct option
I, II and III
I, III and IV
I, II and IV
II, III and IV
B.
I, III and IV
Statement II is incorrect and can be corrected as the basement membrane is present outside the endothelium and is composed of meshwork of collagen. This Glomerular Basement Membrane (GBM) of the kidney is the basal lamina layer of the glomerulus.
The glomerulus capillary endothelial cells, the GBM and the filtration slits between the podocytes perform the filtration function of the glomerulus, separating the blood in the capillaries from the filtrate that forms in Bowman's capsule.
