Question
Identify the membrane across which the proton (H+) gradient facilitates ATP synthesis in a typical eukaryotic cell
plasma membrane
mitochondrial inner membrane
mitochondrial outer membrane
nuclear membrane
Solution
B.
mitochondrial inner membrane
According to chemiosmotic hypothesis, put forward by Mitchell, the electron transfer chain present on the inner mitochondrial membrane generates an electrochemical proton concentration gradient across the membrane. This gradient works as the driving force for ATP synthesis.
