Question
Which proteolytic enzyme induces lysis of fibrin during fibrinolysis ?
Fibrin
Thrombin
Plasmin
Platelet factor-VII
Solution
C.
Plasmin
In fibrinolysis, a fibrin clot, the product of coagulation is broken down. Plasmin is a proteolytic enzyme in plasma which can digest many proteins through the process of hydrolysis. It cuts the fibrin mesh at various places, leading to production of circulating fragments which are cleared by other proteases or by the kidney and liver. It induces lysis of fibrin during fibrinolysis and is known as fibrinolysin
