Question
An example of competitive inhibition of an enzyme is the inhibition of:
succinic dehydrogenase by malonic acid
cytochrome oxidase by cyanide
hexokinase by glucose-6-phosphate
carbonic anhydrase by carbon dioxide
Solution
A.
succinic dehydrogenase by malonic acid
In competitive inhibition, an inhibitor that resembles the normal substrate binds to the enzyme, usually at the active site and prevents the substrate from binding.
An example of competitive inhibition of an enzyme is the inhibition of succinic dehydrogenase by malonic acid. It is the simple type of competitive inhibition. A competitive inhibitor resembles the substrate and binds to the active site of the enzyme. The substrate is then prevented from binding to the same active site.
