Question
Which of the following is the connecting link between glycolysis and Krebs cycle?
Acetyl Co- A
Oxalosuccinic acid
Pyruvic acid
Citric acid
Solution
A.
Acetyl Co- A
Glycolysis is the first step of respiration in which glucose is broken down to pyrurate.
During glycolysis 1 molecule of glucose is converted to 2 molecules of pyruvic acid in the cytoplasm. These two molecules of pyruvic acid are then converted to acetyl Co-A by decarboxylation. This acetyl Co-A is the connecting link between glycolysis and Kreb's cycle and functions as substrate entry for Kreb's cycle. Acetyl Co-A thus formed participates in Kreb's cycle and combines with oxaloacetic acid to form citrate.
