Question
Angiotensinogen is a protein produced and secreted by
-
macula densa cells
-
endothelial cells (cells lining the blood vessels)
-
liver cells
-
juxtaglomerular (JG) cells
Solution
C.
liver cells
Angiotensinogen is a plasma protein produced and secreted by the liver cells. Renin secreted from juxtaglomerular cells and acts enzymaticaly on angiotensinogen to release 10 amino acid peptide angiotensin I.
Macula densa is actually a plaque in wall at the end of thick assending limb of nephrons.