Question
Which of the following does not favour the formation of large quantities of dilute urine?
-
Alcohol
-
Caffeine
-
Renin
-
Atrial-natriuretic factor
Solution
C.
Renin
Renin secreted by JGA regulates the glomerular filtration rate by inducing multihormonal system i.e. RAAS (Renin Angiotensin - Aldosterone System). Activation of this system increase the reabsorption rate of sodium (Na+) and water, making the urine more concentrated.
Alcohol decreases vasopressin level which lowers reabsorption of water thus making urine more dilute. ANF causes vasodilation and acts as check on RAAS