Question
Describe. lock and key hypothesis.
Solution
Lock and key hypothesis. The hypothesis was put forwarded by Fischer (1894).
1. According to this hypothesis the enzyme and its substrate have a complementary shape like that of a lock and key.
2. The specific substrate molecules are bound to specific region of the enzyme molecule called active site. Just as particular lock can be opened by a particular key specially designed to open it, similarly enzymes have specific sites where a particular substrate can only be attached.
