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Cell Cycle And Cell Division

Question
CBSEENBI11003260

At what stage of the cell cycle are histone proteins synthesized in a eukaryotic cell?

  • During entire prophase

  • During telophase

  • During S-phase

  • During G2 stage of prophase

Solution

C.

During S-phase

Histone proteins are basic proteins used for the packaging of eukaryotic DNA. Both DNA and histones together comprise of chromatin, forming bulk of eukaryotic chromosomes. There are 5 major kinds of histones- H1, H2A, H2B, H3 and H4

H1 histone is used for linking neighbouring chromosomes while others are used as elements of nucleosomes structure. During S- phase of cell cycle, synthesis of histone proteins takes place as the chromosome number gets doubled to that of somatic number.