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Chemistry In Everyday Life

Question

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Which forces are involved in holding the drugs to the active site of enzyme.

Solution

Ionic bonding, hydrogen bonding, van dar Waals interactions or dipole-dipole interaction are involved in holding the drugs to the active site of enzymes and receptors.
For example, if amino acid serine is present nearby the substrate held on active site, then its -OH group is free to act as a nucleophile in the enzyme catalysed reaction.

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