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Sponsor Area
1. First gap phase (G1 phase) or presynthetic phase.
2. Synthetic phase (S phase)
3. Second gap phase (G2 phase) or Mitotic phase (M phase)
4. Cell division phase or Mitotic phase (M phase).
The G1, S and G2 phases together constitute the Interphase. This phase takes about 95% of the duration of cell cycle. The mitotic or M phase only lasts for about an hour.
1. G1 phase. This stage starts from the birth of the daughter cell and ends upto the time when the cell begins to synthesis of DNA. It is the phase of initial growth in which RNA and proteins are synthesised. Its duration varies from 6 to 8 hours.
2. S phase. It is the period of synthesis of DNA. It lasts for 5-6 hours.
Fig. Cell cycle
3. G2 phase. During this phase the centrioles, mitochondria, golgi bodies and other cytoplasmic organelles are doubled. Proteins are synthesised for the formation of astral rays and spindle and energy is stored for the cell division or M phase. The duration of this stage starts from the end of S phase upto the beginning of M phase. It lasts for 4-8 hours.
4. M phase or mitosis. It is the phase when the cell division takes place and this process gives rise to two daughter cells. collectively form the cell cycle.
1. It is an equational division. The daughter cells are identical to each other and also to the parent cell in genetic constitution.
2. Mitosis helps in the survival of a species and continuation of its race. It gives a complete set of genetic information to each cell.
3. Mitosis is related to the growth of an individual from zygote to adult stage.
4. It helps in repairing of cells, healing of wounds and regeneration of body cells.
5. It helps in maintaining a specific nucleocytoplasmic ratio in a cell.
1. The ribonuclease enzyme acts as poison at prophase.
2. Mustard gas causes fragmentation and agglutination of chromosomes.
3. Colchicine inhibits the formation of mitotic spindle.
1. Prophase II. It occurs immediately after cytokinesis of meiosis I. The nuclear membrane disaapars and chromosomes become compact.
2. Metaphase II. The chromosomes arrange themselves on the equator. Each chromosome is attached to the spindle fibres of opposite poles by its centromeres. The spindle microtubules from the opposite poles attach to the kinetochores of sister chromatids.
3. Anaphase II. The centromere of each chromosome divides into two sister chromatids. Thus two chromatids of each chromosome move towards opposite poles.
4. Telophase II. The group of young chromosomes at each pole arranges itself into a daughter nucleus. The nuclear membrane is formed. Nucleoli appear and spindles disappear. takes place resulting in the formation of four daughter cells.
2. Formation of spores. Meiosis produces spores in plants for asexual reproduction.
3. Maintenance of chromosome number. Meiosis reduces the chromosome number in the gametes so that fertilization may restore the original diploid number in the zygote.
4. Introduction of variations. Meiosis provides a chance for the formation of new combinations of alleles and chromosomes. This brings about variations which cause evolution. The new combinations of alleles are produced by crossing-over in prophase-I.
1. The gametic fusion takes place at the time of fertilisation when sperm and ovum fuse to form a diploid zygote.
2. The zygote is divided by mitotic division during its embroynic life and post embryonic life to form a well developed individual.
3. A mature individual produces gametes by gametogensis. Reductional division takes place at this stage and results in the formation of haploid gametes.
Example. If a parent cell has 16 chromosomes then in daughter cells due to meiotic division number of chromosomes is reduced to eight.
Mitosis. It is called equational division because number of chromosomes and amount of DNA in daughter cells remain equal to parent cells.
Example. If a parent cell has 18 chromosomes, then in daughter cells formed by mitosis have each 18 chromosomes.
Significance.- At chiasmata crossing over occurs in pachytene stage. The crossing over brings variations which are raw material of evolution.
Cytokinesis in animal cell |
Cytokinesis in plant cell |
1. It occurs by furrow method. 2. The constriction in plasmalemma is formed by contraction of microfilaments. 3.Cleavage starts at the periphery and then moves inward, dividing the cell into two parts. |
1. It occurs by cell plate method. 2. No constriction is formed. 3. Cell plate formation starts at the centre of the cell and grows outward, toward the lateral walls.
|
Metaphase I |
Metaphase |
1. Tetrads are arranged at equator. 2. Two equatorial plates are formed by centromeres. |
1.Chromosomes are arranged at centre. 2. One equatorial plate is formed by centromeres. |
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Cytokinesis |
Karyokinesis |
1.It is a division of cytoplasm into daughter cells. 2. Stages such as prophase, metaphase, anaphase, and telophase are not present in cytokinesis. |
1. It is division of nucleus into daughter nuclei 2. It is divided into four stages: prophase, metaphase, anaphase, and telophase |
1. Chromosomes are moved to spindle equator.
2. Centromere splits and chromatids separate.
3. Pairing between homologous chromosomes takes place.
4. Crossing over between homologous chromosomes takes place.
1. Synapsis
2. Bivalent
3. Chiasmata.
Draw diagrams to illustrate your answer.
2. Bivalent : A pair of homologous chromosomes is called bivalent.
3. Chiasmata : It is point in a tetrad where crossing over occurs.
Discuss with your teacher about.
1. haploid insects and lower plants where cell division occurs, and
2. Some haploid cells in higher plants where cell division does not occur.
1. Male bees, wasps and ants are haploid as they are produced from unfertilized eggs.
2. Synergids and antipodal cells do not divide.
Whereas, the primary oocyte divide to form ootid and polar bodies of unequal size.
1. Number of chromosomes per cell.
2. Amount of DNA content (C) per cell.
Mitosis | Meiosis |
1. Equational division. Chromosome number remains the same in the daughter cells. |
1. Reduction division. Chromosome number is resuced to half in the daughter cell. |
2. Occurs in somatic cells |
2. Occurs in germ cells. |
3. Occurs in both sexually and asexually reproducing organisms. |
3. Occurs only in sexually reproducing organisms. |
4. No crossing over takes place. |
4. Crossing over takes place during pachytene stage. |
5. Prohase is simple and not divided into sub stages. | 5. Prohase I of meiosis I is complex and has 5 stages. |
Interphase is the resting stage of the cell cycle. It covers 95% of the total duration of a cell cycle. It involves a series of changes that prepare a cell for division. It is the period during which the cell experiences growth and DNA replication in an orderly manner. Interphase is divided into three phases.
(i) G1 phase
(ii) S phase
(iii) G2 phase
G1 phase - It is the interval between mitosis and initiation of DNA replication. It is the stage during which the cell grows and prepares its DNA for replication. In this phase, the cell is metabolically active but there is no replication of the DNA.
S phase - It is known as the synthesis phase as it is the stage during which DNA synthesis occurs. In this phase, the amount of DNA (per cell) doubles, but the chromosome number remains the same.
G2 phase - In this phase, the cell continues to grow and prepares itself for the division. The proteins and RNA required for mitosis are synthesised during this stage.
The G0 or quiescent phase is the inactive stage that some cells enter in the adult animals. the stage is characterised by cells that do not exhibit division or proliferation but are metabolically active. They only proliferate when called on to do so depending on the requirement of the organism.
Anaphase of Mitosis | Anaphase I of Meiosis |
The chromatids separate and move to the opposite poles. | The chromatids remain associated. |
Centromeres split. | Centromeres do not split. |
What is the significance of meiosis?
Meiosis is the reduction division the reduction in the amount of genetic material.
Significance of meiosis
1. Meiosis maintains the chromosome number from generation to generation. It reduces the chromosome number to half so that the process of fertilisation can restore the original number in the zygote.
2. It has an evolutionary importance as it allows variations to occur. The process of cross-over and the random distribution of homologous chromosomes between daughter cells result in variation in the genetic make-up of the cells. Variations play an important role in evolution.
3. Chromosomal mutations are brought about by the introduction of certain inheritable changes which may be advantageous for an individual.
Microtubules are the constituent of
spindle fibres, centrioles and cilia
centrioles, spindle fibres and chromatin
centrosome, nucleosomes and centrioles
cilia, flagella and peroxisomes
A.
spindle fibres, centrioles and cilia
Microtubules are structures present in cilia, flagella, centrioles and spindle fibres. They are also the part of fibres found in cytoskeleton.
A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. there is no formation of cell plate and thus the cell is containing more number of chromosomes as compares to other dividing cells. This would result in
polyploidy
somaclonal variation
polyteny
aneuploidy
A.
polyploidy
Polyploid cells have a chromosome number that is more than double the haploid number.
Which of the following is not a characteristic feature during mitosis in somatic cells?
Disappearance of nucleolus
Chromosome movement
Synapsis
Spindle fibres
C.
Synapsis
Synapsis is pairing of homologous chromosomes. It occurs during zygotene stage of meiosis
Spindle fibres attach on to
kinetochore of the chromosome
centrosome of the chromosome
kinetosome of the chromosome
telomere of the centrosome
A.
kinetochore of the chromosome
Spindle fibres attach to kinetochores of chromosomes during cell division. They help the chromosomes to get separated to the two daughter cells, towards opposite poles.
In meiosis crossing over is initiated at
leptotene
zygotene
diplotene
pachytene
D.
pachytene
Crossing over takes place in pachytene stage.
The complex formed by a pair of synapsed homologous chromosomes is called
equatorial plate
kinetochore
bivalent
axoneme
C.
bivalent
Homologous chromosomes pair up. This process is called synapsis. Each pair is called bivalent. Chromosomes line up around the equator of the spindle, attached by their centromeres to the spindle fibres, which are microtubules. The microtubules forming spindles can be of two types, i.e., kinetochore-microtubule and non-kinetochore microtubule.
Axoneme is the central core of a cilium of flagellum consisting of a central pair of filaments surrounded by nine other pairs. The equatorial plate is the plane located midway between the poles of a dividing cell during the metaphase stage of mitosis or meiosis. It is formed from the migration of the chromosome to the centre of the spindle.
Meiosis takes place in
Meiocyte
Conidia
Gemmule
Megaspore
A.
Meiocyte
In diploid organisms, specialised cells called meiocytes(gamete mother cell) undergo meiosis. Conidia and gemmules are asexual reproductive structures found in penicillium and sponge respectively. Megaspores are female gametes in plants, which undergo sexual reproduction.
The cell -mediated immunity inside the human body is carried out by
T- lymphocytes
B - lymphocytes
thrombocytes
erythrocytes
A.
T- lymphocytes
T - lymphocyte receptors can recognise the only antigen that bound to cell membrane proteins these lymphocytes mediates CMI (cell-mediated immunity). B - lymphocytes are the major effector molecules of humoral immunity. Erythrocytes are red blood cells. Thrombocytes or platelets secrete factors that are involved in the vascular repair.
A stage in cell division is shown in the figure. Select the answer which gives correct identification of the stage with its characteristics
Telophase |
Nuclear envelope reforms, Golgi complex reforms |
Late anaphase |
Chromosomes move away from equatorial plate, Golgi complex not present |
Cytokinesis |
Cell plate formed, Mitochondria distributed between two daughter cells |
Telophase |
Endoplasmic reticulum and nucleolus not reformed yet |
A.
Telophase |
Nuclear envelope reforms, Golgi complex reforms |
Telophase is the reserve of prophase. The chromosome that has reached their respective polar decondense and their individually. Late anaphase is characterised by centromeres split and chromatid moves to opposite poles. Cytokinesis is processed in which cell itself is divided two daughter cells.
Arrange the following events of meiosis in correct sequence:
(a) Crossing over
(b) Synapsis
(c) Terminalisation of chiasmata
(d) Disappearance of nucleolus
(b), (a,) (d), (c)
(b), (a) (c), (d)
(a), (b) (c), (d)
(b), (c) (d), (a)
B.
(b), (a) (c), (d)
The correct sequence of events of meiosis are:
Synapsis in zygotene Crossing over in pachytene
Terminalisation of chiasmata in diplotene
Disappearance of nucleolus in diakinesis.
During which phase (s0 of the cell cycle, the amount of DNA in a cell remains at the 4C level if the initial amount is denoted as 2C?
Go and G1
G1 and S
Only G2
G2 and M
D.
G2 and M
During the S or synthetic phase, the DNA content double, i,e, from 2C to 4C for all diploid cells. The G2 phase follows the S-phase and is called second growth phase or pre-mitotic gap phase. In G2 phase the synthesis of DNA stops, therefore, the DNA level remains 4C if initial was 2C
However, the formation of RNA and protein continues as they are required for the multiplication of cell organelles, spindle formation and cell growth. This amount becomes, half (i.e,) 2C only during anaphase (in mitosis) when chromosomes separate.
In human females, meiosis-II is not completed until?
puberty
fertilization
uterine implantation
birth
B.
fertilization
In human females, meiosis-II is not completed until fertilisation. Secondary oocyte is arrested in metaphase-II stage until sperm cell contacts plasma membrane of the oocyte and completes meiosis II resulting in release of ovum.
During gamete formation, the enzyme recombinase participates during
metaphase - I
anaphase-II
prophase-I
prophase-II
C.
prophase-I
The pachytene stage of prophase I of meiosis I is characterized by the appearance of recombination nodules, the sites at which crossing over occurs between non-sister chromatids of the homologous chromosomes. Crossing over is the exchange of genetic material between two homologous chromosomes. It is also an enzyme-mediated process and the enzyme involved is called recombinase.
In S - phase of the cell cycle
amount of DNA dobles in each cell
amount of DNA remains same in each cell
chromosome number is increased
amount of DNA is reduced to half in each cell
A.
amount of DNA dobles in each cell
S-phase is the synthesis phase in which the cell synthesis a replica of its gerome, i.e., DNA replication occurs by DNA polymerase.
DNA replication along with the synthesis of histone proteins results in the duplication of chromosomal material i.e., amount of DNA doubles in each cell.
Amount of DNA remains unchanged during G1 pahse or post mitotic gap and /or G2 phase pre mitotic phase.
Given below is the representation of a certain event at a particular stage of a type of cell division. Which is this stage?
Prophase-I during meiosis
Prophase-II during meiosis
Prophase of mitosis
Both prophase and metaphase of mitosis
A.
Prophase-I during meiosis
The figure shows zygotine stage of prophase-I of meiosis-I. During this stage, bivalent chromosomes clearly appear as tetrads, Pachytene stage is characterized by the appearance of recombination nodules, the sites at which crossing over (exchange of genetic material) occurs between non-sister chromatids of the homologous chromosomes.
Identify the meiotic stage in which the homologous chromosomes separate while the sister chromatids remain associated at their centromeres
metaphase I
metaphase II
anaphase I
anaphase II
C.
anaphase I
In anaphase - I of meiosis homologous chromosomes separate and pass towards different poles of the spindle creating two haploid sets of chromosomes.
During anaphase-II of meiosis centromere of two chromatids of a chromosome separate. The separated chromatids become independent daughter chromosome.
A somatic cell that has just completed the S phase of its cell cycle, as compared to gamete of the same species, has
twice the number of chromosomes and four times the amount of DNA
same number of chromosomes but twice the amount of DNA
twice the number of chromosomes and four times the amount of DNA
four times the number of chromosomes and twice the amount of DNA
C.
twice the number of chromosomes and four times the amount of DNA
In general a gamete contains 'n' number of chromosomes (haploid) and 'x' amount of DNA. In comparison to the gamete, an (diploid) somatic cell usually have 2n number of chromosomes and 2x amount of DNA. But, after the cell enters and complete the 'S'-phase of its cell cycle, the DNA content of the cell becomes double (due to its duplication). However, the number of chromosomes remains the same. Hence, the somatic cell that has undergone and completed its 'S' phase of cell cycle will have twice the number of chromosomes and four times the DNA content.
Chromosomes | DNA content | |
Gamete | n | x |
Somatic cell (diploid) | 2n | 2x |
Somatic cell (after S-phase) | 2n | 4x |
What would be the number of chromosomes of the aleurone cells of a plant with 42 chromosomes in its root tip cells?
63
84
21
42
A.
63
The outermost cell layer of the endosperm (3n) of seed is called aleurone layer. Since the cells of aleurone layer are triploid, the number of chromosomes would be = 63, as root tip cells (2n) has 42 chromosomes.
Select the correct option with respect to mitosis
Chromatids start endoplasmic
Golgi complex and endoplasmic reticulum are still visible at the end of prophase
chromosomes move to the spindle equator and get aligned along equatorial plate in metaphase
chromatids separate but remains in the centre of the cell in anaphase
C.
chromosomes move to the spindle equator and get aligned along equatorial plate in metaphase
In metaphase of mitosis, spindle fibres attach to kinetochore of chromosomes. Chromosomes are moved to spindle equator and get aligned along meta phasic plate through spindle fibres to both poles.
At metaphase, chromosomes are attached to the spindle fibres by their
satellites
Secondary constrictions
Kinetochores
centromere
C.
Kinetochores
Kinetochores ar small disc -shaped proteinous structures present at the surface of the centromere. These structures serve as the sites of attachment of spindle fibres to the chromosomes that are moved into position at the centre of the cell.
During mitosis ER and nucleolus begin to disappear at
late prophase
early metaphase
late metaphase
early prophase
D.
early prophase
In mitosis, prophase is the longest phase of karyokinesis.In early prophase, nuclear membranes, nucleolus start disintegrating. cells cytoskeleton, Golgi complex, ER, etc disappear.
Which stages of cell division do the following figures A and B represent respectively?
Metaphase - Telophase
Telophase - Metaphase
Late anaphase - Prophase
Prophase - Anaphase
C.
Late anaphase - Prophase
Late anaphase is characterised by following events;
i) Centromeres split and chromatids separate.
ii) Chromatids move to opposite poles.
Prophase is characterised by centriole separation.
In the hexaploid wheat, the haploid (n) and basic (x) numbers of chromosomes are
n = 7 and x = 21
n = 21 and x = 21
n = 21 and x = 14
n = 21 and x = 7
D.
n = 21 and x = 7
The basic (x) number of chromosome of hexaploid wheat is 7 and haploid (n) number is 21.
What would be the number of chromosomes in the cells of the aleurone layer in a plant species with 8 chromosomes in its synergids?
16
24
32
8
B.
24
Synergids are two, short-lived, haploid cells lying close to the egg in nature embryosac of flowering plant ovule. While the endosperm is a triploid tissue formed after triple fusion. Thus, if the synergids have 8 chromosomes, the aleurone layer (part of endosperm) will have just triple of that of chromosomes in the synergids i.e, 24 chromosomes.
Which of the following options gives the correct sequence of events during mitosis?
Condensation - nuclear membrane disassembly
- crossing over - segregation - telophase
Condensation - nuclear membrane disassembly
-arrangement at equator - centromere
division - segregation - telophase
Condensation - crossing over - nuclear
membrane disassembly - segregation -
telophase
Condensation - arrangement at equator -
centromere division - segregation -
telophase
B.
Condensation - nuclear membrane disassembly
-arrangement at equator - centromere
division - segregation - telophase
The correct sequence of events during mitosis would
be as follows
(i) Condensation of DNA so that chromosomes become visible occurs during early to mid-prophase.
(ii) Nuclear membrane disassembly begins at late prophase or transition to metaphase.
(iii) Arrangement of chromosomes at equator occurs during metaphase, called congression.
(iv) Centromere division or splitting occurs during anaphase forming daughter chromosomes.
Zygotic meiosis is characteristic of
Marchantia
Fucus
Funaria
Chlamydomonas
D.
Chlamydomonas
Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
Chromosomes will not condense
Chromosomes will be fragmented
Chromosomes will not segregate
Recombination of chromosome arms will occur
C.
Chromosomes will not segregate
Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes during anaphase. If APC is defective then the chromosomes will fail to segregate during anaphase.
DNA replication in bacteria occurs
During S-phase
Within nucleolus
Prior to fission
Just before transcription
C.
Prior to fission
DNA replication in bacteria occurs prior to fission. Prokaryotes do not show well marked S-phase due to their primitive nature
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Select the incorrect match :
Lampbrush – Diplotene bivalents chromosomes
Allosomes – Sex chromosomes
Polytene chromosomes – Oocytes of amphibians
Submetacentric chromosome – L-shaped chromosomes
C.
Polytene chromosomes – Oocytes of amphibians
Polytene chromosomes are found in salivary glands of insects of order Diptera.
Which of the following events does not occur in rough endoplasmic reticulum?
Protein folding
Protein glycosylation
Phospholipid synthesis
Cleavage of signal peptide
C.
Phospholipid synthesis
Phospholipid synthesis does not take place in rough endoplasmic reticulum (RER). Smooth endoplasmic reticulum are involved in lipid synthesis.
Select the wrong statement :
Cell wall is present in members of Fungi and Plantae
Mushrooms belong to Basidiomycetes
Mitochondria are the powerhouse of the cell in all kingdoms except Monera
Pseudopodia are locomotory and feeding structures in Sporozoans
D.
Pseudopodia are locomotory and feeding structures in Sporozoans
Pseudopodia are locomotory structures in sarcodines (Amoeboid).
Post-mitotic gap phase is characterised by all, except
Synthesis of RNA and nucleotides
No change in DNA content
Synthesis of histone proteins
Growth phase of the hell
C.
Synthesis of histone proteins
Post-mitotic gap phase is characterised by all except the synthesis of histone proteins. Histone proteins are synthesised in S-phase. S-phase is called invisible phase of the cell cycle as replicated chromosomes are not visible at this stage.
Independent assortment of gene occurs due to the orientation of chromosomes at
Metaphase-I of mitosis
Metaphase-I of meiosis
Metaphase-II of meiosis
Any phase of the cell division
B.
Metaphase-I of meiosis
The independent assortment of the gene occurs due to the orientation of chromosomes at late metaphase - I of meiotic cell division at the time of gamete formation.
The non-disjunction, in meiosis may result is extra copy of a chromosome in a sperm cell. During which phase the above phenomenon may occur?
Prophase-I, prophase-II
Prophase-I, prophase-II
Anaphase-I, anaphase-II
Anaphase-I, telophase-II
C.
Anaphase-I, anaphase-II
In anaphase-I and II chromosomes become shorter and thicker and migrate towards opposite poles of the cell. In case of non-disjunction of chromosomes, an extra copy of a chromosome will be present in the cell.
The mitotic cell cycle is divided typically into four phases; G1, S, G2 and M. Considering a mitotic cycle time of 18 hrs; the distribution of period of time (in hrs) for each of these phases will be
G1 | S | G2 | M |
1 | 3 | 5 | 9 |
G1 | S | G2 | M |
9 | 1 | 3 | 5 |
G1 | S | G2 | M |
9 | 5 | 3 | 1 |
G1 | S | G2 | M |
3 | 5 | 9 | 1 |
C.
G1 | S | G2 | M |
9 | 5 | 3 | 1 |
The longest phase of cell cycle in G1 where these rapid growths and metabolic activity, followed by S phase for DNA synthesis and replication then G2 phase for preparation of cell division and lastly mitotic phase.
therefore, Ratio is 9:5:3:1
Which one of the following precedes re-formation of the nuclear envelope during M-phase of the cell Cycle?
Decondensation from chromosome and reassembly of the nuclear lamina
Transcription from chromosome and reassembly of the nuclear lamina
Formation of the contractile ring and formation of the phragmoplast
Formaltion of the contractile ring and transcription from chromosomes
A.
Decondensation from chromosome and reassembly of the nuclear lamina
At telophase stage, nuclear membrane vesicles associate with the surface of individual chromosomes and fuse to reform the nuclear membranes, which partially enclose clusters of chromosomes before coalescing to reform the complete nuclear envelope. During this process, the nuclear pores reassemble and the dephosphorylated reassociate to form the nuclear lamina) One of the lamina proteins (lamina-B) remains with the nuclear membrane fragments throughout mitosis and may help nucleate assembly. After the nucleus reforms, the pores pump in nuclear proteins, the chromosome decondense and RNA synthesis resume, causing the nucleolus to reappear.
Viruses that infect bacterial multiplication and cause their lysis, are called
Lysozymes
Lipolytic
Lytic
Lysogenic
C.
Lytic
When bacteriophage infects a bacterium, it entirely depends on the host for its multiplication. It utilises the host machinery for replication and produce a large number of progeny phage particles. The bacterium cell undergoes lysis and dies to liberate a large number of these phage particles, which are each ready to start another cycle by infecting new bacterial cell. This cycle is known as lytic cycle.
During meiotic division, the
homologous chromosomes are seperated
linkage is disturbed
homologous chromosomes do not segregate
All of the above
A.
homologous chromosomes are seperated
Meiotic division occurs in reproductive system or germ cells. After meiosis, four haploid cells are present which are not identical to their parents. Homologous chromosomes form bivalent by pairing and each of them is seperated. They move towards the opposite poles of the spindle fibres. Each daughter cell receives a haploid set of chromosomes.
During the G1- phase of cell division
RNA and proteins are synthesised
DNA and proteins are synthesised
cell prepares for M- phase
cell undergoes duplication
A.
RNA and proteins are synthesised
Cell division has two phases:
(a) Karyokinesis- Nucleus division.
It is further divided into-
(i) Interphase is a resting phase and consists of G1, S and G2 phase.
Phase | Activities |
G1 | RNA and protein synthsis takes place |
S | DNA replication takes place |
G2 | Damaged DNA is repaired and division of centrosomes takes place |
(ii) M- phase represnts the phase of actual division
(b) Cytokinesis- Cytoplasm division.
In cell cycle, during which phase chromosomes are arranged in equatorial plate?
Metaphase
Anaphase
Telophase
Prophase
A.
Metaphase
Metaphase in both mitosis and meiosis is characterized by the arrangement of chromosomes on the spindle fibres at the equatorial plate.
Prophase is the longest phase. In this phase, chromatin of nucleus becomes condensed forming chromosomes.
Anaphase is the phase where the separation of chromatids takes place. It moves in the opposite direction towards the pole and is the shortest phase of all.
Telophase is the last phase. In this phase, chromatin network are reformed, nuclear membrane and nucleolus reappears.
Mitotic spindle have main protein
tubulin
myosin
tropomyosin
dynein
A.
tubulin
The mitotic spindle is a highly dynamic molecular machine composed of tubulin, motors and other molecules. It assembles around the chromosomes and distributes the duplicated genome to the daughter cells during mitosis.
Microtubules are unbranched, hollow, sub- microscopic tubules, which form the structural material of cilia, flagella, basal bodies, centrioles and spindle apparatus. They are built up protofilaments, formed of two related proteins, and - tubulins.
Crossing over occurs in
zygotene
leptotene
pachytene
diplotene
C.
pachytene
Crossing over, ie, exchange of segments between non- sister chromatids of homologous chromosome occurs in pachytene stage of Prophase- I of Meiosis- I.
Number of chromosomes in an angiospermic plant is 14, then the number of chromosomes in synergid cells will be
14
7
28
21
B.
7
The number of chromosomes in root cells is 2n while it is n in synergids because it develops by reductional division.
Therefore, the number of chromosomes in synergid cells is 7.
At what stage of the cell cycle are histone proteins synthesized in a eukaryotic cell?
During entire prophase
During telophase
During S-phase
During G2 stage of prophase
C.
During S-phase
Histone proteins are basic proteins used for the packaging of eukaryotic DNA. Both DNA and histones together comprise of chromatin, forming bulk of eukaryotic chromosomes. There are 5 major kinds of histones- H1, H2A, H2B, H3 and H4.
H1 histone is used for linking neighbouring chromosomes while others are used as elements of nucleosomes structure. During S- phase of cell cycle, synthesis of histone proteins takes place as the chromosome number gets doubled to that of somatic number.
In meiosis division is
Ist reductional and IInd equational
Ist equational and IInd reductional
both reductional
both equational
A.
Ist reductional and IInd equational
The term 'Meiosis' was given by Farmer and Moore (1905). To study meiosis in plants, anther is the best part.
The process of meiosis involves two division of the genetic material. The first division is called reduction division or Meiosis I as it reduces the number of chromosomes from 46 chromosomes or 2n to 23 chromosomes or n.
Meiosis II is called equational division because it does not reduce chromosome numbers. A nuclear division that maintains the same ploidy level of the cell.
Colchicine prevents the mitosis of the cells at which of the following stage?
Anaphase
Metaphase
Prophase
Interphase
B.
Metaphase
Colchicine, an alkaloid obtained from Colchincum autumnale (Liliaceae), prevents mitosis by inhibiting spindle formation through disruption of microtubules. It is a mitotic poison.
Which typical stage is known for DNA replication?
Metaphase
G1- phase
S- phase
G2- phase
C.
S- phase
S- phase or Synthesis phase is the phase of the cell cycle in which DNA is replicated. It occurs between G1 and G2 phase.
During this phase, DNA is replicated and histones are sythesized so that each chromosomes becomes two chromatids.
The term 'Meiosis' was given by
Johansen
Knoll and Ruska
A. Flemming
Farmer and Moore
D.
Farmer and Moore
Farmer and Moore (1905) proposed the term meiosis. Meiosis is a type of cell division that results in four daughter cells each with half the number of chromosomes of the parent cells, as in production of gametes and plant spores.
Lampbrush chromosomes are seen in which typical stage
mitotic anaphase
mitotic prophase
mitotic metaphase
meiotic prophase
D.
meiotic prophase
Lampbrush chromosomes are a special form of chromoosme found in the growing oocytes of most animals, except mammals. They grow profusely during prophase of meiosis- I.
The checkpoint in cell cycle plays important role in
repairing DNA damage
apoptosis initiation
assessing DNA damage
none of these
C.
assessing DNA damage
A checkpoint is one of several points in the eukaryotic cell cycle at which the progression of a cell to the next stage in the cycle can be halted until conditions are favourable.
The checkpoint in cell cycle plays important role in
repair DNA damage
apoptosis initiation
assess DNA damage
inhibit cell damage.
C.
assess DNA damage
A checkpoint is one of several points in the eukaryoticcell cycle at which the progression of a cell to the next stage in the cycle can be halted until conditions are favorable.
Barr Body is found in the cytoplasm during
interphase in cell of female mammal
interphase in cell of male mammal
prophase in cell of female mammal
prophase in cell of male mammal.
A.
interphase in cell of female mammal
Barr body is also known as sex chromatin or X chromatin. Barr body is partially inactivated and development of this facultative heterochromatin occurs in one of the two X chromosomes in interphase nuclei of human female. Any of the two X-chromosomes can become heterochromatin.
Which is the longest phase of the cell cycle
M-phase
interphase
Leptotene
S-phase
B.
interphase
Cell cycle is divided into 2 phases.
(i) Interphase (a period of preparation for cell division)
(ii) M phase (the actual period of cell division).
The interphase cell is metabolically quite active. Interphase is the long nondividing phase further divided into G1, S and G2. It occupies 75 to 95% of entire cell division time.
When synapsis is complete all along the chromosome, the cell is said to have entered a stage called
zygotene
pachytene
diplotene
diakinesis
B.
pachytene
Prophase I consists of 5 stages:
(i) Leptotene- Chromosomes become gradually visible.
(ii) Zygotene- Synapsis, pairing of homlogous chromosomes takes place. It results in the formation of bivalents. Also, formation of special proteinaceous structure called synaptonemal complex occur.
(iii) Pachytene- Cells that eneterd this phase results in spiralling, shortening and thickening of the bivalents.
(iv) Diplotene- Dissolution of synaptonemal complex takes place. Also, recombined homologous chromosomes of the bivalents seperate.
(v) Diakinesis- Terminalisation of chiasmata occur in this phase.
The importance of meiosis lies in :
bringing discontinuous variations
addition in the number of chromosomes
reduction in the number of chromosomes
maintaining the number of chromosomes
D.
maintaining the number of chromosomes
Meiosis is a type of cell division that results in 4 daughter cells each with half the number of chromosomes of the parent cell. It maintains the fixed number of chromosomes in sexually reproducing organisms. It produces haploid gametes by reducing the chromosome number to half. These gametes on fertilization restore diploidy.
In mitotic cell division, the division of centromere and the division of chromatid occurs between
anaphase and telophase
prophase and metaphase
telophase and interphase
anaphase and metaphase
D.
anaphase and metaphase
In metaphase, chromosomes align at the metaphase plate and sister chromatids attach to spindle fibres from opposite poles.
In anaphase, centromeres divide and chromatids move to opposite poles. This is known as the separation of sister chromatids.
Spindle chromosomes have
centriole
kinetochore
chromocentre
chromomere
B.
kinetochore
As prometaphase ends and metaphase begins, the chromosomes align along the cell equator. Every chromosome has at least two microtubules extending from its kinetochore — with at least one microtubule connected to each pole. At this point, the tension within the cell becomes balanced, and the chromosomes no longer move back and forth. In addition, the spindle is now complete, and three groups of spindle microtubules are apparent. Kinetochore microtubules attach the chromosomes to the spindle pole; interpolar microtubules extend from the spindle pole across the equator, almost to the opposite spindle pole; and astral microtubules extend from the spindle pole to the cell membrane.
In mitosis the duplication of chromosomes occurs during
early prophase
late prophase
interphase
late telophase
C.
interphase
S phase is the early phase of cell cycle. S phase (Synthesis Phase) is the phase of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase. Since accurate duplication of the genome is critical to successful cell division, the processes that occur during S-phase are tightly regulated and widely conserved.
Bivalents in meiosis are
tetrad
pairs of non-homologous chromosomes
pairs of several chromatids
pairs of homologous chromosomes
A.
tetrad
A bivalent, sometimes referred to as a tetrad, is the association of a pair of homologous chromosomes physically held together by at least one DNA crossover. This physical attachment allows for alignment and segregation of the homologous chromosomes in the first meiotic division.
In which stage of the first meiotic division, each chromosome undergoes longitudinal division to give rise to two sister chromatids ?
Zygotene
Diplotene
Diakinesis
Pachytene
D.
Pachytene
Pachytene is a stage of first meiotic division in which the chromosomes appear further thickened due to coiling and divides longitudinally into two sister chromatids.
Which of the following sequence is a correct one for meiotic cell cycle?
G1 S G2 M G1
G1 G2 S M G2
G2 G1 S M G2
S G1 G2 M S
A.
G1 S G2 M G1
The basic parts of cell cycle are interphase and M-phase or dividing phase. The interphase is metabolically the most active stage and divided into G1, S and G2 phases. The correct sequence of phases in cell cycle is
G1 S G2 M G1
Chromosomes replicate in which stage of meiosis?
Prophase- I
Prophase- II
Telophase- I
Interphase
D.
Interphase
Interphase is a phase of cell cycle where cell prepares itself for division. It consists of 3 phases: G1 phase, S phase and G2 phase.
During S or Synthesis phase, all the chromosomes get replicated. Each chromosome consists of two sister chromatids.
In eukaryotic DNA, histone and non- histone proteins are known as chromatin. It consists of thread- like structures known as chromosomes. Hence, the replication of DNA in the chromosomes initiates in S- phase of interphase.
In which stage of cell division chromosomes are most condensed
Prophase
Metaphase
Anaphase
Telophase
C.
Anaphase
'Anaphase', is the stage of mitosis after the metaphase when replicated chromosomes are split and the daughter chromatids are moved to opposite poles of the cell. Chromosomes also reach their overall maximum condensation in late anaphase, to help chromosome segregation and the re-formation of the nucleus.
Which phase comes in between the G1 and G2 phases of cell cycle?
M - phase
G0 - phase
S - phase
Interphase
C.
S - phase
Cell cycle is a series of events that take place in a cell leading to duplication of its DNA and division of cytoplasm and organelles to produce two daughter cells.
Interphase has 3 stages: G1 phase, S- phase and G2 phase. S or synthesis phase is a the stage where DNA starts replication.
Cell division cannot be stopped in which phase of the cell cycle?
G1- phase
G2- phase
S- phase
Prophase
B.
G2- phase
Cell division can not be stopped G2 phase of the cell cycle.
Cells in G0 phase of cell cycle
exit cell cycle
enter cell cycle
suspend cell cycle
terminate cell cycle
C.
suspend cell cycle
The G0 phase or resting phase is a period in the cell cycle in which cells exist in a quiescent state. G0 phase is viewed as either an extended G1 phase, where the cell is neither dividing nor preparing to divide, or a distinct quiescent stage that occurs outside of the cell cycle.
Longest phase of meiosis
prophase- I
prophase- II
anaphase- I
metaphase- II
A.
prophase- I
Meiosis is a division necessary for the formation of gametes in animals and spores in plants. Prophase- I is longest phase of meiosis and composed 5 sub phases which are leptotene, zygotene, pachytene, diplotene and diakinesis.
In which stage of the first meiotic division two sister chromatids are formed?
Leptotene
Zygotene
Pachytene
Diplotene
C.
Pachytene
In pachytene substage of meiosis- I the paired homologous chromosomes divide into two sister chromatids. Thus, each bivalent is composed of four chromatids and known as tetrad.
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The correct sequence of different phases of cell cycle is
S - G1 - G2 - M
G1 - S - G2 - M
G2 - S - G1 - M
G1 - G2 - S - M
B.
G1 - S - G2 - M
The complete cell cycle contains a sequence of phases which are
(a) Interphase which is further subdivided into G1-phase or postmitotic gap, S-phase or synthesis phase and G2-phase or premitotic gap respectively
(b) Dividing phase or M-phase (mitotic or meiotic phase) which comprises karyokinesis and cytokinesis.
So, the correct sequence of phases in cell cycle is
G1 S G2 M
The complex formed by a pair of synapsed homologous chromosomes is called
equatorial plate
kinetochore
bivalent
axoneme
C.
bivalent
Synapsis is the pairing of homologous chromosomes. Each pair is called bivalent. Chromosomes line up around the equator of the spindle, attached by their centromeres to the spindle fibres, which are microtubules. The microtubules forming spindles can be of two types, i.e., kinetochore microtubule and non-kinetochore microtubule.
Axoneme is the central core of a cilium or flagellum consisting of a central pair of filaments surrounded by nine other pairs.
Equatorial plate is the plane located midway between the poles of a dividing cell during the metaphase stage of mitosis or meiosis. It is formed from the migration of the chromosome to the centre of the spindle.
Meiosis takes place in
Meiocyte
Conidia
Gemmule
Megaspore
A.
Meiocyte
In diploid organisms, specialised cells called meiocytes or gamete mother cell undergo meiosis. Conidia and gemmules are asexual reproductive structures found in Penicillium and sponge respectively. Megaspores are female gametes in plants, which undergo sexual reproduction.
A stage in cell division is shown in the figure. Select the answer which gives correct identification of the stage with its characteristics
Telophase - Nuclear envelope reforms, Golgi complex reforms
Late anaphase - Chromosomes move away from equatorial plate, Golgi complex not present
Cytokinesis - Cell plate formed, mitochondria distributed between two daughter cells
Telophase - Endoplasmic reticulum and nucleolus not reformed yet
A.
Telophase - Nuclear envelope reforms, Golgi complex reforms
Telophase is the phase in which chromosomes are no longer seen and each set of chromatin material tends to collect at each of the two poles.
Late anaphase is characterised by centromeres split and chrorratid separate and chromatid move to opposite poles.
Cytokinesis is process in which cell itself is divided two daughter cells.
Select the correct statement related to mitosis.
Amount of DNA in the parent cell is first halved and then distributed into two daughter cells
Amount of DNA in the parent cell is first doubled and then distributed into two daughter cells
Amount of DNA in the parent cell is first halved and then distributed into four daughter cells
Amount of DNA in the parent cell is first doubled and then distributed into four daughter cells
B.
Amount of DNA in the parent cell is first doubled and then distributed into two daughter cells
Mitosis is a type of division in which the chromosomes replicate themselves and gets equally distributed into two daughter cells, i.e., the amount of DNA in this gets doubled first and then distributed into two daughter cells. This is actually a cloning in which daughter cells produced are identical to the parent cells and receive equal number of chromosomes.
Proteins helping in kinetocore formation of yeast are
CBF2 and Kar3 P
CBF2 and CBF3
CBF3 and Kar3 P
CBF2, CBF3 and Kar3 P
D.
CBF2, CBF3 and Kar3 P
The kinetochore assembles on the centromere and links the chromosome to microtubule polymers from the mitotic spindle during mitosis and meiosis. Its proteins also help to hold the sister chromatids together and play a role in chromosome editing. CBF2, CBF3 and Kar3P are the kinetocore proteins used in yeast. These three are the proteins which are commonly called as factors. These proteins helps in the binding of the chromosome to the microtubules by attachment with different complexes.
Which one of the following is wrong for meiosis?
It leads to formation of sister chromatids
It occurs in diploid cell
It occurs in haploid cell
It occurs by splitting of centromeres and separation of sister chromatids
C.
It occurs in haploid cell
Meiosis is a specialised and much complicated type of cell division, occurring only in the formation of haploid sex cells (sperm and ovum). The gametes, after the process of fertilisation, restore the original diploid number by forming the zygote.
Which of the followings does not occur in the interphase of eukaryotic cell division?
Increase of ATP synthesis
Increase of DNA synthesis
Increase of RNA synthesis
Reduction in cell size
D.
Reduction in cell size
Interphase is the living phase of the cell. Here, cell spends its majority of time and prepares itself for cell division. This increases its size and makes a copy of its DNA. Majority of eukaryotic cells spends most of their time in interphase.
Match the item in column I with those in column II and the choose the correct answer.
Column I | Column II |
A. Mitosis | 1. Occurs in diploid cells only |
B. Meiosis | 2. Occurs in both haploid and diploid cells |
3. Daughter and parent cells have same chromosome numbers | |
4. Synapsis of homologous chromosomes. |
A- 1; B- 2
A- 2; B- 3
A- 3; B- 4
A- 4; B- 1
C.
A- 3; B- 4
Column I | Column II |
A. Mitosis | 3. Daughter and parent cells have same chromosome numbers. |
B. Meiosis | 4. Synapsis of homologous chromosomes occurs |
During mitosis nuclear membrane disappears at
early prophase
late prophase
metaphase
anaphase
B.
late prophase
In mitosis, during late prophase or prometaphase, nuclear membrane completely disappear while mutant form is observed rarely.
Spindle fibres of mitotic cell are made up of
tubulin
actin
myosin
collagen
A.
tubulin
Spindle fibres are formed during cell division. These are made up of tubulin. Each tubulin molecule is made up of a. and B sub-units. Tubulin molecules are attached heat to tail and form a strand and 13 strands aggregate to form a microtubule. These microtubules are attached to kinetochores of. metaphase chromosomes and play an important role in the movement of chromosomes during subsequent stages of cell division.
During meiosis crossing over occurs at
pachytene
zygotene
leptotene
diakinesis
A.
pachytene
During pachytene stage, crossing over takes place. It is exchange of equal segments of non-sister chromatids belonging to homologous chromosomes. The chromosome pair (i.e. bivalent) consists of four chromatids and thus crossing over takes place at four stranded stage.
During meiosis crossing over occurs between which part of homologous chromosome ?
Sister chromatids
Non-sister chromatids
Genes
Alleles
B.
Non-sister chromatids
Crossing over is the exchange of chromosomal segments between non-sister chromatids of homologous chromosomes. It occurs in pachytene stage of meiotic division-I.
In cell cycle, during, which phase chromosomes are arranged in equatorial plate ?
Metaphase
Anaphase
Telophase
Prophase
A.
Metaphase
Metaphase in both meiosis and mitosis is characterized by the orientation of chromosomes themselves on the spindle fibres at the equatorial plate.
In prophase, chromatin of the nucleus become condensed forming chromosomes. Chromosome replication occurs in prophase.
Anaphase is characterized by the separation of chromatids.
Telophase in a sense is a reversible process of prophase.
In synapsis two homologous chromosomes are connected at
centromeres
chromomeres
telomeres
none of these
B.
chromomeres
The synapsis is the pairing of two homologous chromosomes. The pairing is exact. The pairing may begin from centromere or from ends of chromosomes.
Stages in proper sequence of prophase- I are
zygotene, leptotene, pachytene, diakinesis
leptotene, zygotene, pachytene, diplotene and diakinesis
eptotene, pachytene, zygotene, diakinesis and diplotene
diplotene, diakinesis, pachytene, zygotene and leptotene
B.
leptotene, zygotene, pachytene, diplotene and diakinesis
Prophase I is the longest phase of Meiosis. Recombination takes place or croosing over. It includes 5 sub- phases, which are as follows-
1. Leptotene
2. Zygotene
3. Pachytene
4. Diplotene
5. Diakinesis
The stage of cell cycle when cell has undergone differentiation is :
G0
G1
G3
G4
A.
G0
G0 is the phase which undergoes differentiation. It is also known as quiscent phase.
DNA/chromosome replication takes place during:
G1- phase
G2- phase
S- phase
Prophase
C.
S- phase
Replication of DNA and synthesis of histone protein takes place during S- phase. At the end of S phase, each chromosome has two DNA molecules, i.e., a duplicate set of genes.
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