Sponsor Area
The vertebral column is differentiated
into
i. Cervical (7),
ii. Thoracic (12),
iii. Lumbar (5),
iv. Sacral (1-fused) and
v coccygeal (1-fused) regions starting from the skull.
The bones of the legs are:
i. Femur
ii. Tibia
iv. Fibula
iv. Tarsals
v. Metatarsals
vi Phalanges
Sponsor Area
On the basis of location the muscles can be of three types :
i. Skeletal.
ii Visceral and
iii. Cardiac.
Sponsor Area
A motor neuron alongwith the muscle fibres connected to it constitute a motor unit.
The junction between a motor neuron and the sarcolemma of the muscle fibre is called the neuromuscular junction or motor-end plate.
What is the location of visceral muscles
Visceral muscles are located in the inner walls of hollow visceral organs of the body like the alimentary canal, reproductive tract, etc.
Osteoporosis is the age-related disorder characterised by decreased bone mass and increased chances of fractures. It is common in females as decreased levels of estrogen is a common cause.
The cardiac muscles are striated in appearance. They are involuntary in nature as the nervous system does not control their activities directly.
The two occipital condyles (dicondylic skull) help in the articulation of the skull region with the superior region of the vrtebral column.
Skeletal system : It forms the main supporting frame work of the body. It consists of the framework of bones and a few cartilage. The system plays a major role in the movement of the body.
The human skeletal system is made up of 206 bones and a few cartilages. It is divided in to two main categories.
A. Axial skeleton : It is present on median longitudinal axis of body e.g. skull, vertebral column, sternum, ribs etc. It comprises of 80 bones.
i. The skull - is composed of two sets of bones cranial and facial, that totals to 22 bones. Cranial bones are 8 in number.
ii. The vertebral colummn - is formed by 26 serially arranged units called vertebrae and is dorsally placed. It extends from the base of the skull and constitutes the main framework of the trunk. Each vertebra has a central hollow portion (neural canal) through which the spinal cord passes.
iii. Sternum is a flat bone on the ventral midline of thorax.
iv. Ribs - There are 12 pairs of ribs. Each rib is a thin flat bone connected dorsally to the vertebral column and ventrally to the sternum. The first 7 pairs are called True ribs, the 8th, 9th and 10th are called False ribs, and the 11th and 12th are called Floating ribs.
B. Appendicular skeleton : It is present on sides and present in appendages and associated with them. It includes the bones of the limbs and the pectoral girdles, pelvic girdles.
i. Bones of the limbs - each limb is formed of 30 bones. The bones of the hand are humerus, radius and ulna, carpals (8), metacarpals (5) and phalanges (14).
The leg is made up of Femur, tibia and fibula, tarsals (7) metatarsals (5) and phalanges (14). A cup shaped bone called patella cover the knee ventrally (knee cap).
ii. Pelvic and pectoral girdle - Pectoral and Pelvic girdle bones help in the articulation of the upper and the lower limbs respectively with the axial skeleton. Each girdle is formed of two halves. Each half of pectoral girdle consists of a clavicle and a scapula. Pelvic girdle consists of two coxal bones. Each coxal bone is formed by the fusion of three bones – ilium, ischium and pubis.
Skull : It has two sets of bones - the cranial and facial, that totals to 22 bones. Cranial bones are 8 in number. They form the hard protective outer covering, cranium for the brain. The facial region is made up of 14 skeletal elements which form the front part of the skull. A single U-shaped bone called hyoid is present at the base of the buccal cavity and it is also included in the skull.
A. Cranium : It encloses the brain. Cranium has following eight bones :
(a) Frontal bone (one)
(b) Parietal bones (two)
(c) Occipital bone (one)
(d) Temporal bones (two)
(e) Sphenoid bone (one)
(f) Ethmoid bone (one)
B. Bones of face : Face has fourteen bones namely :
(a) Nasals (two)
(b) Maxilla (two)
(c) Palatines (two)
(d) Mandible (one)
(e) Zygomatic bones or cheek bones (two)
(f) Inferior nasal conchae (two)
(g) Vomer (one)
(h) Lacrimal (two)
1. It protects the brain from injuries.
2. It helps in the movement of lower jaw.
3. It helps in the protection of eyes.
4. It helps in the protection of internal ear.
Function of ribs :
1. It protects the vital organs and blood vessels
2. It expands and contracts along with the lungs to allow for efficient breathing
Ribs : There are twelve pairs of ribs. The ribs are of three types :
1. True ribs : There are seven pairs of true ribs. At one end they are attached to vertebral column and at the second end they are attached to sternum.
2. False ribs : There are three pairs of false ribs. At one end these are attached to vertebral column and at second end these get attached to each other.
3. Floating ribs : There are two pairs of floating ribs. These are attached to vertebral column and the second end is free.
Sternum : It lies in the centre in thoracic region on ventral sides. It is a flat bone on the ventral midline of thorax.
Functions of sternum :
1. It provides the position for the attachment of ribs.
2. It takes part in the formation of rib cage which protects the heart and lungs.
Vertebral column : It is formed by 26 serially arranged units called vertebrae and is dorsally placed. It extends from the base of the skull and constitutes the main framework of the trunk. central hollow portion (neural canal) through which the spinal cord passes. It has a central hollow portion (neural canal) through
which the spinal cord passes. The vertebral column is differentiated into cervical (7), thoracic (12), lumbar (5), sacral (1-fused) and coccygeal (1-fused) regions starting from the skull. The number of cervical vertebrae are seven in almost all mammals including human beings. The vertebral column protects the spinal cord, supports the head and serves as the point of attachment for the ribs and musculature of the back. The vertebrae are divided into following categories :
1. Cervical vertebrae : These are present in neck. These are seven in number (All mammals have seven cervical vertebrae).
2. Thoracic vertebrae : These are present in thoracic region. There are twelve thoracic vertebrae.
3. Lumbar vertebrae : These are present in abdominal region and are five in number.
4. Sacral vertebrae : There are five sacral vertebrae present in pelvic region. These get fused to form one sacrum.
5. Coccygeal vertebrae : These are four in number and are present below sacrum. These fuse to form one vertebra.
Functions of vertebral column :
1. It protects the spinal cord.
2. It supports head.
3. It provides erect posture, balance and stability for the body.
4. It provides attachment points for the ribs, pelvic bones, and many muscles.
5. Allows for flexibility and mobility.
6.Supports the structure and weight of the body in various activities.
Pectoral girdle : The pectoral girdle is formed of two halves. Each half consists of a clavicle and a scapula .
1. Scapula is a large triangular flat bone situated in the dorsal part of the thorax between the second and the seventh ribs. The dorsal, flat, triangular body of scapula has a slightly elevated ridge called the spine which projects as a flat, expanded process called the acromion. Below the acromion is a depression called the glenoid cavity which articulates with the head of the humerus to form the shoulder joint.
2. Clavicle is collar bone. It is a slender bone with two curvatures.
Pelvic girdle or Hip girdle : It consists of two coxal bones. Each coxal bone is formed by the fusion of three bones – ilium, ischium and pubis. At the point of fusion of the above bones is a cavity called acetabulum to which the thigh bone articulates. The two halves of the pelvic girdle meet ventrally to form the pubic symphysis containing fibrous cartilage.
Function of pelvic girdle.
1. It provides space for attachment of bones of hind limbs.
2. It provides movement to hind limbs.
3. The muscles of hind limbs are inserted into pelvic girdles.
4. It provides protection to abdominal viscera.
Bones of forelimb : Each limb is made of 30 bones.
A. Forelimbs - There are two forelimbs each having thirty bones.
These are :
i. Humerus — (1)
ii. Radius-ulna — (2)
iii. Carpals — (8)
iv. Metacarpals — (5)
v. Phalanges — (14)
B. Hindlimb : There are two hindlimbs. Each hindlimb has thirty bones.
These are :
i. Femur — (1)
ii. Patella — (1)
iii. Tibia-fibula —(2)
iv. Tarsdals — (7)
v. Metatarsals — (5)
vi. Phalanges — (14)
ii. Hinge joint joint - In this type of joint -surface of one bone articulates with concave surface of another. It is found between the carpals.
iii. Saddle joint - Each bone in a saddle joint resembles a saddle, with concave and convex portions that fit together. It is found between the carpal and metacarpal of thumb.
iv. Pivot joint. - This joint consist of the rounded end of one bone fitting into a ring formed by the other bone. It is found between atlas and axis.
v. Gliding joint - It is formed between bones that meet at flat or nearly flat articular surfaces In this type of joint the It is found between the carpals
Dislocation : When a bone is displaced from its specific position, then it is said to be dislocated and the phenomenon is called dislocation of bone.
Fractures : A fracture is a complete or incomplete break in a bone resulting from the application of excessive force
Types of movements :
The cells of our human body display three types of movements, namely amoeboid, ciliary and muscular.
i. Amoeboid movement - Cells like macrophages and leucocytes in the blood exhibit amoeboid movement. Cytoskeletal elements like microfilaments are also involved in amoeboid movement.
ii. Ciliary movement - is shown by cells of our internal tubular organs which are lined by ciliated epithelium. The coordinated movements of cilia in the trachea help us in removing dust particles and some of the foreign substances inhaled alongwith the atmospheric air. Passage of ova through the female reproductive tract is also facilitated by the ciliary movement.
iii. Muscular movements - is shown by our limbs, jaws, tongue, etc, require muscular movement. The muscular movement is used for locomotion and other movements by human beings and majority of multicellular organisms.
Explain Muscular Fatigue
Muscular fatigue : is the decline in ability of a muscle to generate force. It can be a result of vigorous exercise but abnormal fatigue may be caused by barriers to or interference with the different stages of muscle contraction. It happens when the muscles respire anaerobically and produce lactic acid. The accumulation of lactic acid leads to fatigue.
Answer the following briefly :
(a) How does a muscle shorten during its contraction and lengthen during its relaxation?
(b) What biological functions are served by the skeletal system ?
(c) Why a red muscle fibre can work for a prolonged period while a white musule fibre suffers from fatigue after a shorter work ?
(b) Functions of skeletal system :
1. It provides mechanical support.
2. It protects the essential organs as heart, brain, spinal cord etc.
3. It plays role in breathing.
4. It helps in locomotion.
5. It checks entry of food into glottis at the time of swallowing of food.
(c) Red muscle fibres contain myoglobin which stores oxyen as oxymyoglobin and it also has more number of mitochondria. Due to sufficient supply of oxygen little lactic acid is formed. These muscles contract slowly and remain in the contracted state for a long time. TDue to more energy and less lactic acid these muscles do not fatigue in less time.
White muscle fibres have no myoglobin. So, lactic acid is formed in them. Moreover, their contraction is fast, thus they get fatigued.
Skeletal muscle is made of a number of muscle bundles or fascicles that our held together by a common collagenous connective tissue layer called fascia.
ii. Each muscle bundle contains a number of muscle fibres.
iii. Each muscle fibre is lined by the plasma membrane known as sarcolemma enclosing the sarcoplasm.
iv. Since the muscle fibre's sarcoplasm contains many nuclei it is caleed as a is a syncitium.
v. The sarcoplasmic reticulum of the muscle fibres is the store house of calcium ions.
vi. The muscle fibre has a large number of parallelly arranged filaments in the sarcoplasm called myofilaments or myofibrils.
vii. Each myofibril has alternate dark and light bands on it. The striated appearance is due to the distribution pattern of Actin and Myosin proteins. The light bands contain actin and is called I-band or Isotropic band, whereas the dark band called ‘A’ or Anisotropic band contains myosin.
viii. In the centre of each ‘I’ band is an elastic fibre called ‘Z’ line . The thin filaments are firmly attached to the ‘Z’ line. The thick filaments in the ‘A’ band are also held together in the middle of this band by a thin fibrous membrane called ‘M’ line.
ix. The ‘A’ and ‘I’ bands are arranged alternately throughout the length of the myofibrils. The portion of the myofibril between two successive ‘Z’ lines is considered as the functional unit of contraction and is called a sarcomere.
A muscle cramp is a sudden and involuntary contraction of one or more muscles. They are usually characterised by pain and swelling.
Hypertrophy : Increase in the size of muscles is called hypertrophy. Increase in the size of muscle may occur due to exercise. Due to repeated and forceful contraction of muscles, mass of muscle increases and so does the number of mitochondria, filaments in sarcomeres and amount of sarcoplasm.
Atrophy : Decrease in the size of muscle is called atrophy. Atrophy is due to immobilization of muscles. Mass of muscles decreases due to decrease in number of mitochondria, filaments in sarcomeres and amount of sarcoplasm. An injury to a nerve which supplies a muscle can also cause atrophy
The striated appearance is due to the distribution pattern of two important proteins – Actin and
Myosin. The light bands contain actin and is called I-band or Isotropic band, whereas the dark band called ‘A’ or Anisotropic band contains myosin proteins. The proteins are arranged as rod-like structures, parallel to each other and also to the longitudinal axis of the myofibrils. Actin filaments are thinner while the myosin filaments, are thicker. An elastic fibre called ‘Z’ line which bisects the I band. The thin filaments are firmly attached to the ‘Z’ line. The thick filaments in the ‘A’ band are also held together in the middle of this band by a thin fibrous membrane called ‘M’ line. The ‘A’ and ‘I’ bands are arranged alternately throughout the length of the myofibrils.
How are the thick and thin filaments arranged ?
Thin or Actin filaments :
The light bands contain actin and is called I-band or Isotropic band, whereas the dark band called ‘A’ or Anisotropic band contains myosin. Actin filaments are thinner and are called thin filaments. The myosin filaments are called thick filament. The thick filaments in the ‘A’ band are also held together in the middle of this band by a thin fibrous membrane called ‘M’ line. The ‘A’ and ‘I’ bands are arranged alternately throughout the length of the myofibrils.
Sponsor Area
Each actin filament is made of two ‘F’ or filamentous actins. These are helically wound to each other. The ‘F’ actin is a polymer of monomeric
‘G’ (Globular) actins. Two filaments of another protein, tropomyosin are also present close to the ‘F’ actins throughout its length. Troponin a complex protein is found at regular intervals on the tropomyosin.
Smooth Muscle Fibres :
Occurrence : They are present in the walls of hollow visceral organs like stomach, intestine, lungs, arteries, veins, urinary bladder etc.
Shape : Spindle shaped with narrow or pointed ends.
Structure : TheThey do not exhibit any striations and are snooth in appearance. The unstriped muscle fibres may occur singly or may occur in groups and form sheets. Each unstriped muscle fibre is bounded by plasmalemma. The sarcoplasm contains an oval nucleus in centre. It also has number of myofibrils but without light and dark bands. These muscle fibres contract slowly and relax slowly that is why they do not get fatigued.
The muscles are not under the control of the nervous system and hence are called involuntary muscles.
Functions - They muscle assist, for example, in the transportation of food through the digestive tract and gametes through the genital tract.
Cardiac Muscle Fibres :
Occurrence : They are present in myocardium of heart.
Structure : Each cardiac muscle fibre is bounded by plasmalemma. They are separated from each other by intercalated discs. These intercalated discs act as boosters. The adjacent muscle fibres are connected by oblique cross walls. The cardiac muscle fibre has deep in centre a slightly oval nucleus. The myofibrils are present and have light and dark bands. The cardiac muscle fibres have abundant blood supply that is why they are of dark red colour. These fibres contract quickly and take double the time to relax and that is why they never feel fatigued.
Control : They are controlled by central and autonomic nervous system.
There are 3 main types of muscles.
1. Striated muscle fibres or skeletal muscles.
2. Unstriped or smooth muscle fibres or visceral muscles.
3. Cardiac muscles
Discuss the mechanism of muscular contraction.
Mechanism of muscular contraciton :
The Sliding filament theory explains the movement of the muscles. The theory was given by A.F. Huxley
According to this theory actin and myosin filaments slide past each other with the help of cross bridges to reduce the length of sarcomere and actin filaments which meet in centre of sarcomere.
1. When the stimulus of a motor nerve reaches neuromuscular junction then the vesicles present in the synaptic knobs secrete Acetyl choline which diffuses into sarcomere through membrane channel of muscle fibre.
Na+ also flow through channel into sarcomere and results action potential.
2. The muscle fibre which is polarised, after receiving acetyl choline becomes depolarised at that end.
3. The wave of depolarisation spreads due to invagination of sarcolemma called T tubes and Z lines.
4. Due to depolarisation, the sarcoplasmic reticulum secretes Ca+2 ions which bind to specific site present on troponin component of actin filament. Conformational changes occur in Troponin molecule and active sites of F actin molecules are exposed where the cross bridge of myosin filaments gets joined to actin filaments.
5. The cross-bridges take energy from ATP and get rotated inward. Thus sarcomeres contract as Z-lines come closer.
6. Finally whole muscle contracts and H-lines disappear.
7. ADP molecules take energy from creatine~ phosphate and get converted into ATP.
8. The cross-bridges which have been rotated inward may rotate more after taking more energy from ATP molecule. Thus it brings more contraction of sarcomere.
Fig. Relationship between the actin and myosin myofilaments in the (A) relaxed and (B) contracted states
Osteoporosis :
Definition : It is reduction in bone tissue mass causing weakness of skeletal strength (G. osteon = bone, pros = pore, oisis = condition.)
Factors :
1. Excessive resorption of Ca+2 from bones : It results from excessive resorption of calcium and phosphorus from the bone, which leads to vertical compression or crush fracture of the vertebrae.
2. Menopause and Ca+2 absorption : Osteoporosis occurs in postmenopausal women and elderly men. It may result from defective intestinal calcium absorption.
3. Environmental factors : Possible environmental factors include smoking, excessive drinking and decreased exercise. Osteoporosis is more common in women than in men, and in old than middle aged persons.
4. Sex hormones : Imbalances of some hormones, thryocalcitonin, parathormone etc also cause osteoporosis.
5. Vitamin D : Deficiency of vitamin D causes osteoporosis.
The movements and locomotion are neccessary among the animals because of following reasons :
1. Need for searching of shelter, food and water.
2. To escape from predators.
3. For shifting to favourable environment from an unfavourable one.
4. The movemenets of alimentary canal help in movement of food from one part of alimentary canal to next.
5. The ciliary movements help in the meovement of ova in fallopian tubes.
6. Movements of diaphragm and ribs help in breathing.
7. Movement of vocal cords help in the production of sound.
Role of calcium in muscle contraction When the muscle fibre is depolarized then Sarcoplasmic Reticulum releases calcium ions which bind with specific site present on troponin component of actin filament. Increase in Ca++ level leads to the binding of calcium with a subunit of Troponin on actin filaments and thereby remove the masking of active sites for myosin. Utilising the energy from ATP hydrolysis, the myosin head now binds to the exposed active sites on actin to form a cross bridge. Thus, sarcomere contracts .
Joints are the point of contact between bones or between bones and cartilages.
Role of joints in movement :
2. They help in locomotion and many other movements.
3. They help to connect a bone to a bone allowing movemnt.
Actin |
Myosin |
1. It is thin low molecular weight filamentous protein present in the sarcomere. |
1. It is thick filamentous protein present in the sarcomere. |
2. It occurs in two forms the monomeric G-actin and polymeric F-actin. |
2. Each myosin molecule has two components—a tail and head. The tail is formed of heavy meromyosin (HMM) while the head is formed of light meroyosin LMM. |
3. The contractile protein called tropomyosin. |
3. The head has contractile property. |
4. It does not act as ATPase |
4. The head acts as ATPase. |
Red muscle |
White muscle |
1. Myoglobin content is high | 1. Myoglobin content is very less. |
2. Appear red in colour. | 2. Appear white in colour. |
3. Have aerobic respiration and utilise large amount of oxygen. | 4. Carry out anaerobic process and produce energy. |
4. Amount of sarcoplasmic reticulum is low. | Amount of sarcoplasmic reticulum is high. |
5. More number of mitochondria. | 5. very few number of mitochondria. |
Muscle twitch - Muscle twitching is also called muscle fasciculation. Twitching involves small muscle contractions in the body.
Whereas
Tetany - Tetany is rapid spasm in the muscle due to low Ca++ in body fluid.
Immovable Joints |
Movable Joints |
These are immovable joints and called surtures. |
These are freely movable joints. |
Bones are held together by dense fixed joints. |
Bones are not fused with bands of fibres. |
Has no fluid. Pubic symphysis, between canial bones. |
Has synovial fluid in synovial cavity. e.g. Shoulder and hip joint. |
|
Tendons |
Ligaments |
1. Structure : |
Made up of white fibrous connective tissue. |
Made up of yellow fibrous tissue. |
2. Arrangement of fibroblasts : |
In rows between the bundles of white fibres. |
Found scattered in matrix. |
3. Nature : |
Tough and inflexible. |
Elastic and flexible. |
4. Function : |
Join bones to muscles. |
Join bones together. |
(a) A-band |
I-band |
1.Anisotropic band |
Isotropic band. |
2. Dark in appearance and hence also called dark band. |
Light in appearance and hence called light band. |
3. It contains myosin. |
It contains actin . |
(c) Striped Muscles |
Unstriped Muscles |
Cardiac Muscles |
1. Present in limbs, neck tongue etc. |
Present in walls of the hollow organs. |
Present in myocardium of heart |
2. Myofibrils are very conspicuous in them. |
Inconspicuous in them. |
Myofibrils conspicuous in them. |
They have less blood supply. |
They have abundant blood supply. |
They have abundant blood supply. |
Voluntary. |
Involuntary. |
Involuntary. |
These are controlled by central nervous system. |
These are controlled by autonomic nervous system. |
These are controlled by brain and autonomic nervous system. |
Cylindrical in shape. |
These are spindle in shape. |
These are subcylinderical in shape. |
These are multinucleate. |
These are uninucleate. |
These are uninucleate. |
Oblique cross walls are absent. |
Oblique cross walls are absent. |
Oblique cross walls are present. |
Intercalated discs Absent |
Absent |
Present |
Fig. Human Skull
Fig. Ribs and Rib Cage
Vertebral Column
Types of movements in cells of human body : The different types of movements exhibited by the cells of human body :
1. Amoeboid movement : Some specialised cells in our body like macrophages and leucocytes in blood exhibit amoeboid movement. ln this type the movement is done by the formation of pseudopodia by the streaming of protoplasm (as in Amoeba). Cytoskeletal elements like microfilamens are also involved in amoeboid movement.
2. Ciliary movement : Ciliary movement occurs in most of our internal tubular organs which are lined by ciliated epithelium. The coordinated movements of cilia in the trachea help in removing dust particles and some of the foreign substances inhaled along with the atmospheric air. Passage of ova through the female reproductive tract is also facilitated by the ciliary movement.
3. Muscular movement : Movement of our limbs, jaws, tongue etc. require muscular movement. The contractile property of muscles are effectively used for locomotion and other movements by human beings and majority of multicellular organisms. Locomotion requires a perfect coordinated activity of muscular, skeletal and neural.
A.
Actin is present in thin filament.B.
H-zone of striated muscle fibre represents both thick and thin filaments.C.
Human skeleton has 206 bones.D.
There are 11 pairs of ribs in man.E.
Sternum is present on the ventral side of the body.A. Smooth muscle | (i) Myoglobin |
B. Tropomyosin | (ii) Thin filament |
C. Red muscle | (iii) Sutures |
D. Skull | (iv) Involuntary |
A. Smooth muscle | (i) Involuntary |
B. Tropomyosin | (ii) Thin filament |
C. Red muscle | (iii) Myoglobin |
D. Skull | (iv) Sutures |
Name the type of joint between the following:
(a) atlas/axis
(b) carpal/metacarpal of thumb
(c) between phalanges
(d) femur/acetabulum
(e) between cranial bones.
(f) between pubic bones in the pelvic girdle.
Pectoral girdle |
Pelvic girdle |
1. It is present in shoulder. |
1. It is present in hip. |
2. Helps in the articulation of the lower limbs. |
2. Helps in the articulation of the lower limbs. |
3. It is formed of clavicle and a scapula. |
3. It is formed of two coxal bones. Each coxal bone is a fusion of three bones ie ileum, ischium and pubis. |
4. It has glenoid cavity. |
4. It has acetabulum cavity. |
5. Pubic symphysis is absent. |
5. Pubic symphysis is present between two pelvic girdles. |
Myosin filament : Each myosin (thick) filament is a polymerised monomeric proteins. The monomeric units are called Meromyosins. These constitute make one thick filament.
Each meromyosin has two important parts, a globular head with a short arm and a tail, the former being called the heavy meromyosin (HMM) and the latter, the light meromyosin (LMM). The HMM component, i.e.; the head and short arm projects outwards at regular
distance and angle from each other from the surface of a polymerised myosin filament and is known as cross arm. The globular head is an active ATPase enzyme and has binding sites for ATP and active sites for actin.
Thick filament (above) and a myosin molecule (below)
Action filament :
1. Each actin (thin) filament is made of two “F” (filamentous) actins helically wound to each other. Each ‘F’ actin is a polymer of monomelic ‘G’ (Globular) actins.
2. Two filaments of another protein, tropomyosin also run close to the ‘F’ actins throughout its length.
3. A complex protein troponin is distributed at regular intervals on the tropomyosin.
Structure of thick and thin filaments
The sliding filament theory explains the mechanism of muscle contraction. A proposed mechanism of muscle contraction in which the actin and myosin filaments of striated muscle slide over each other to shorten the length of the muscle fibres (see sarcomere). Myosin-binding sites on the actin filaments are exposed when calcium ions bind to troponin molecules in these filaments. This allows bridges to form between actin and myosin, which requires ATP as an energy source. Hydrolysis of ATP in the heads of the myosin molecules causes the heads to change shape and bind to the actin filaments. The release of ADP from the myosin heads causes a further change in shape and generates mechanical energy that causes the actin and myosin filaments to slide over one another
Match Column I with Column II :
A. Smooth muscle | (i) Myoglobin |
B. Tropomyosin | (ii) Thin filament |
C. Red Muscles | (iii) Sutures |
D. Skull | (iv) Involuntary |
A. Smooth muscle | (i) Involuntary |
B. Tropomyosin | (ii) Thin filament |
C. Red Muscles | (iii) Myoglobin |
D. Skull | (iv) Sutures |
Describe the important steps in muscle contraction.
The important steps muscle contraction:
1. Muscle contraction is initiated by a signal sent by the central nervous system (CNS) via a motor neuron and reach the neuromuscular junction. As a result, neurotransmitter (Acetyl choline) which generates an action potential in the sarcolemma.
2. This spreads through the muscle fibre and causes the release of calcium ions into the sarcoplasm.
3. Increase in Calcium level leads to the binding of calcium with a subunit of troponin on actin filaments and thereby remove the masking of active sites for myosin. Utilising the energy from ATP hydrolysis, the myosin head now binds to the exposed active sites on actin to form a cross bridge.
4. The actin filaments are pulled. As a result, the H-zone reduces. It is at this stage that the contraction of the muscle occurs.
5. After muscle contraction, the myosin head pulls the actin filament and releases ADP along with inorganic phosphate. ATP molecules bind and detach myosin and the cross bridges are broken and decreases the calcium ions contraction. As a result, masking the actin filaments and leading to muscle relaxation.
How do you distinguish between a skeletal muscle and a cardiac muscle?
Skeletal Muscle |
Cardiac Muscle |
The cells of skeletal muscles are unbranched. |
The cells of cardiac muscles are branched. |
Intercalated disks are absent. |
The cells are joined with one another by intercalated disks that help in coordination or synchronization of the heart beat. |
Alternate light and dark bands are present. |
Faint bands are present. |
They are voluntary in nature. |
They are involuntary in nature. |
They contract rapidly and get fatigued in a short span of time. |
They contract rapidly but do not get fatigued easily. |
They are present in body parts such as the legs, tongue, hands, etc. |
These muscles are present in the heart and control the contraction and relaxation of the heart. |
Lack of relaxation between successive stimuli in sustained muscle contraction is known as
fatigue
tetanus
tonus
spasm
B.
tetanus
Tetanus results in sustained muscular spasms. This is due to muscle fatigue.
Which type of tissue correctly matches with its location?
Tissue | Location |
Areolar tissue | Tendons |
Tissue | Location |
ATransitional epithelium | Teip of nose |
Tissue | Location |
Cuboidal epithelium | Tlining of stomach |
Tissue | Location |
Smooth muscle | Wall of intestine |
D.
Tissue | Location |
Smooth muscle | Wall of intestine |
Columnar epithelium is present in the stomach lining.
Tendon is dense connective tissue and connects muscle to bone.
Tip of nose consists of elastic cartilage.
The H -zone in the skeletal muscle fibre is due to
the absence of myofibrils in the central portion of A-band
the central gap between myosin filaments in the A-band
the central gap between actin filaments extending through myosin filaments in the A-band
extension of myosin filaments in the central portion of the A-band
C.
the central gap between actin filaments extending through myosin filaments in the A-band
H-zone in skeletal muscle is the central gap between actin filaments extending through myosin filaments in the A -band. Alternate myosin filaments in the A-band. An alternate arrangement of dark and light bands gives the striated appearance to a skeletal muscle. At the centre of A-band, a comparatively less dark zone called H -zone is present. In the centre of H-zone, M -line is present, formed by the threats that connect the myofilaments.
Sponsor Area
Select the correct statement with respect to locomotion in humans
A decreased level of progesterone cause osteoporosis in old people
Accumulation of uric acid crystals in joints causes their inflammation.
The vertebral column has 10 thoracic
The joint between adjacent vertebrae is a fibrous joint.
B.
Accumulation of uric acid crystals in joints causes their inflammation.
Inflammation of joints due to the accumulation of uric acid crystals is gout.The fibrous joint is formed by the flat skull bones, which fuse end - to -end with the help of dense fibrous connective tissue in the form of sutures to form cranium. The vertebral column is formed by 26 serially arranged units called vertebral. The less secretion of progesterone cause abortion as it basically supports a pregnancy.
The characteristics and an example of a synovial joint in humans is
Characteristics |
Examples |
Fluid cartilage between two bones, limited movements |
Knee joints |
Characteristics |
Examples |
Fluid filled between two joints, provides cushion |
Skull bones |
Characteristics |
Examples |
Fluid filled synovial cavity between two bones |
Joint between atlas and axis |
Characteristics |
Examples |
Lymph filled between two bones, limited movement |
Gilding joint between carpals |
C.
Characteristics |
Examples |
Fluid filled synovial cavity between two bones |
Joint between atlas and axis |
The joint between atlas an axis in the pivot, which is an example of synovial joint characterised by the presence of a fluid -filled the synovial cavity between the articulating surface of the two bones. Knee joint (hinge joint) is a synovial joint characterised by the presence of fluid-filled synovial cavity between the articulating surface of the two Bones. Fluid cartilage between two bones having limited movements is slightly movable joint. In freely movable joints fluid filled between two joints provides a cushion in gliding joint. the articulating bones can slide upon another.
Which of the following joints would allow no movement?
Fibrous joint
Cartilaginous joint
Synovial Joint
Ball and Socket joint
A.
Fibrous joint
Fibrous joints are immovable joints in that occur between the bones of the cranium and in the tooth sockets. They do not allow movement because the bones are held firmly together by bundles of strong white collagen fibres. The immovable joints are often known as the sutures. The periosteum that covers the bones dips between them as a septum
Which of the following is not a function of the skeletal system?
Production of erythrocytes
Storage of minerals
Production of body heat
Locomotion
C.
Production of body heat
Production of body heat is the function of muscles. The contraction of muscle produce heat, which keeps the body warm during the winters.
Select the correct matching of the type of the joint with the example in human skeletal system
Types of joint |
Example |
Cartilaginous joint |
Between frontal and parietal |
Types of joint |
Example |
Pivot joint |
Between third and fourth cervical vertebrae |
Types of joint |
Example |
Hinge joint |
Between humerus and pectoral girdle |
Types of joint |
Example |
Gliding Joint |
Between carpals |
D.
Types of joint |
Example |
Gliding Joint |
Between carpals |
Gliding joint is a type of synovial joint, found between carpal bones and tarsal bones.
The cartilaginous joint between surfaces of skull bones. The pivot joint is found between the atlas and axis. Hing joint is found in the elbow, knee ankle and interphalangeal joint.
Stimulation of a muscle fibre by a motor neuron occurs at
the neuromuscular junction
the transverse tubules
the myofibril
the sarcoplasmic reticulum
A.
the neuromuscular junction
Stimulation of a muscle fibre by a motor neurone occurs at neuromuscular junction neuron activated a muscle to contract during the excitation-contraction coupling of vertebrate skeletal muscles
Select the correct statement regarding the specific disorder of muscular or skeletal system
Muscular dystrophy-age related shortening of muscles
Osteoporosis-decrease in bone mass and higher chances of fractures with advancing age
Myasthenia gravis-Auto immune disorder which inhibits sliding of myosin filaments
Gout-inflammation of joints due to extra deposition of calcium
B.
Osteoporosis-decrease in bone mass and higher chances of fractures with advancing age
Osteoporosis is age-related disease in which bone loose minerals and fibres from the matrix causing decreased bone mass and higher chances of fractures with advancing age. Major causative factors of osteoporosis are imbalance of hormones like calcitonin of thyroid, parathormone of parathyroids, sex hormones and deficiencies of calcium and vitamins.
Glenoid cavity articulates
clavicle with acromotion
scapula with acromion
clavicle with scapula
humerus with scapula
D.
humerus with scapula
Glenoid cavity articulates humerus with scapula. It is a feature on the scapula (shoulder blade or shoulder bone). It is slightly concave from above downwards and from side to side. It is shallow and a site of attachment of glenoid labrum (glenoid ligament), which forms fibrocartilaginous rim around the glenoid cavity. It is important because it has the effect of depending the socket into which head of humerous (bone) rests, forming the shoulder joint). It represents a type of synovial, ball and socket joint.
The type of muscles present in our
heart are involuntary and unstriated smooth muscles
intestine are striated and involuntary
thigh are striated and voluntary
Upper arm are smooth muscle fibres fusiform in shape
C.
thigh are striated and voluntary
Thigh muscles are a skeletal muscle that is striated and voluntary skeletal muscles tissue is closely attached to skeletal bones.
Three of the following pairs of the human skeletal parts are correctly matched with their respective inclusive skeletal category and one pair is not matched. Identify the non -matching pair.
Pairs of skeletal parts |
Category |
Sternum and ribs |
Axial skeleton |
Pairs of skeletal parts |
Category |
Clavicle and glenoid cavity |
Pelvic girdle |
Pairs of skeletal parts |
Category |
Humerus and ulna |
Appendicular skeleton |
Pairs of skeletal parts |
Category |
Malleus and stapes |
Ear ossicles |
B.
Pairs of skeletal parts |
Category |
Clavicle and glenoid cavity |
Pelvic girdle |
Clavicle and glenoid cavity are found in a pectoral girdle. Each half of pectoral girdle consists of the clavicle and a scapula. Glenoid cavity is a depression below the acromion (the expanded process of scapula). The glenoid cavity articulates with the head of the humans to form the shoulder joint.
Which one of the following pairs of structures is correctly matched with their correct description?
Structure |
Description |
Tibia and fibula |
Both form parts of knee joint |
Structure |
Description |
Cartilage and cornea |
No blood supply but do require oxygen for respiratory |
Structure |
Description |
Shoulder joint and elbow joint |
Ball and socket type of joint |
Structure |
Description |
Premolars and molars |
20 in all and 3 rooted |
B.
Structure |
Description |
Cartilage and cornea |
No blood supply but do require oxygen for respiratory |
Cartilage is usually described as a vascular, as the blood vessels innervate only the outer fibrous sheath of cartilage, called perichondrium. The cornea is the transparent anterior portion of the outer coat of the vertebrate eye covering the iris and the pupil. It is avascular as it lacks lymphatic and blood vessels.
Which one of the following is the correct description of a certain part of a normal human skeleton?
Parietal bone and the temporal bone of the skull are joined by fibrous joint
First, vertebra is axis, which articulates with the occipital condyles
The 9th and 10th pairs of ribs are called the floating ribs
Glenoid cavity is a depression to which the thigh bone articulates
A.
Parietal bone and the temporal bone of the skull are joined by fibrous joint
Immovable or fixed or fibrous joints are found between the skull bones. No movement occurs at these joints. So, parietal bone and the temporal bone of the skull are joined by fibrous joint. Invertebrates, the first vertebra is called petals, while the second vertebra is the axis. In humans first pairs of ribs are called true ribs; 8th and 9th and 10th pairs of ribs are false ribs while 11th and 12th pairs of ribs are called floating ribs.
Glenoid cavity is a socket shaped cavity in the scapula (shoulder bone) that holds the head of the humerus in a ball and socket joint.
Elbow joint is an example of
pivot joint
hinge joint
gliding joint
ball and socket joint
B.
hinge joint
In hinge joint, the convex surface of one bone fits into the concave surface of another bone. eg, knee elbow and interphalangeal joints.
Pivot joint, one bone is fixed and second articulated, eg, atlas and axial of skull rotate with axis vertebra.
Gliding joints primarily permit side-by-side and back and forth gliding movements, eg, intercarpal joints and intertarsal joints.
In ball and socket joint, a ball of one bone articulates in sockets of another bone, eg, head of the humerus and glenoid cavity of the pectoral girdle.
Which one of the following are the correct pairing of a body part and the kind of muscle tissue that moves it?
Heart wall - Involuntary unstriated muscle
Biceps of upper arm - smooth muscle fibres
Abdominal wall - Smooth muscle
Iris - Involuntary smooth muscle
D.
Iris - Involuntary smooth muscle
Smooth muscles are plain, non- striated, involuntary or unstriped muscles due to the absence of striations. These occur in the walls of hollow internal organs, in capsules of lymph glands, spleen etc, in iris and ciliary body of eyes, skin dermis, penis and other accessory genitalia etc.
Keeping in view the 'fluid mosaic model' for the structure of cell membrane, which one of the following statements is correct with respect to the movement of lipids and proteins from one lipid monolayer to the other (described as flip-flop moment)?
Both lipids and proteins can flip-flop
While lipids and proteins can flip -flop
While proteins can flip-flop, lipids cannot
Neither lipids, nor proteins can flip-flop
B.
While lipids and proteins can flip -flop
singer and Nicolson (1972) suggested the widely accepted fluid mosaic model of biological membranes. According to this model, the plasma membrane contains a bimolecular lipid layer, both surface of which are interrupted by protein molecules. Some proteins are attached to the polar surface of the lipid (ie, called extrinsic protein) while, other (called intrinsic proteins) either partially entirely to stick but on both sides (called transmembrane proteins). The Movement of lipid molecules from one lipid monolayer to another monolayer is called flip-flop movement. Flip-flop movement is rarely found in lipid molecules whereas it remain absent in protein molecules.
Earthworms have no skeleton but during burrowing, the anterior end becomes turgid and acts as a hydraulic skeleton. It is due to
Coelomic fluid
blood
gut peristalsis
setae
A.
Coelomic fluid
The body cavity (coelom) of an earthworm is filled with an alkaline, colourless or milky coelomic fluid containing water, salts, some proteins and four types of coelomic corpuscles, ie, phagocytes, mucocytes, circular nucleated cells and chloragogen cells. The coelomic fluid becomes turgid and acts as a hydraulic skeleton during burrowing.
Earthworm (Pheretime posthuma) living in burrows which are made in moist earth. It makes its burrow which is made in the moist earth. it makes its burrow partly by boring with its pointed anterior end and partly sucking and swallowing the earth. The body shows metameric segmentation. About the middle of each segment, there is a ring of tiny curved bristles called setae or chaetae, formed of any nitrogenous organic substance known as chitin. The setae and musculature serve for locomotion as well as for anchoring body firmly in the burrow.
The blood of earthworm is composed of a fluid plasma and colourless corpuscles, physiologically comparable to the leucocytes of vertebrates.
Which one of the following items gives its correct total number?
Floating ribs in humans - 4
Amino acids found in proteins - 16
Types of diabetes - 3
Cervical vertebrae in humans -8
A.
Floating ribs in humans - 4
There are 12 pairs of ribs in human, which form the bony lateral walls fo the thoracic cage. The last two pairs of ribs (total four) are called floating ribs because their anterior ends are not attached to either the sternum or the cartilage of another rib. The floating ribs protect the kidneys. There are 7 cervical vertebrae in humans present in the neck. The first cervical vertebra is called atlas second is known as an axis.
There are 20 amino acids found in proteins.
Which of the following is a flowering plant with nodules containing filamentous nitrogen-fixing micro-organism
casuarina equisetifolia
crotalaria juncea
cycas revoluta
cicer arietinum
A.
casuarina equisetifolia
The Casuarina tree has nitrogen fixing root nodules that harbor a filamentous streptomycete like nitrogen fixing organism called Frankia.
Which of the following is an example of negative feedback loop in humans?
constriction of skin blood vessels and contraction of skeletal muscles when it is too cold
secretion of tears after falling of sand particles into the eye
salivation of mouth at the sight of delicious food
secretion of sweat glands and constriction of skin blood vessels when it is too hot
A.
constriction of skin blood vessels and contraction of skeletal muscles when it is too cold
Skin blood vessels constrict and skeletal muscles contract due to cold is an example of negative feedback mechanism of homeostatis.
The contractile protein of skeletal muscle involving ATPase activity is
tropomyosin
myosin
α-actinin
troponin
B.
myosin
The kinesin, myosin and dynein proteins of skeletal muscle involve ATP as activity. This cause the contraction of skeletal muscles, propelling action of cillia and flagella the intracellular transport of organelles.
The pivot joint between atlas and axis is a type of
Fibrous joint
Cartilaginous joint
Synovial joint
Saddle joint
C.
Synovial joint
Synovial joints are freely movable joint which allow considerable movements. Pivot joint is a type of synovial joint which provide rotational movement as in between atlas and axis vertebrae of vertebral column
Out of 'X' pairs of ribs in humans only 'Y' pairs are true ribs. Select the option that correctly represents values of X and Y and provides their explanation :
X = 12, Y = 7
True ribs are attached dorsally to vertebral column and ventrally to the sternum
X = 12, Y = 5
True ribs are attached dorsally to vertebral column and sternum on the two ends
X = 24, Y = 7
True ribs are dorsally attached to vertebral column but are free onventral side
X = 24, Y = 12
True ribs are dorsally attached to vertebral column but are free on ventral side
A.
X = 12, Y = 7
True ribs are attached dorsally to vertebral column and ventrally to the sternum
In human, 12 pairs of ribs are present in which 7 pairs of ribs (1st to 7th pairs) are attached dorsally to vertebral column and ventrally to the sternum
Calcium is important in skeletal muscle contraction because it
Binds to troponin to remove the masking of active sites on actin for myosin.
Activates the myosin ATPase by binding to it.
Prevents the formation of bonds between the myosin cross bridges and the actin filament.
Detaches the myosin head from the actin filament.
A.
Binds to troponin to remove the masking of active sites on actin for myosin.
The signal for contraction increase Ca++ level many folds in the sarcoplasm.
Ca++ now binds with sub-unit of troponin (troponin 'C') which is masking the active site on actin filament and displaces the sub-unit of troponin.
Once the active site is exposed, head of the myosin attaches and initiate contraction by sliding the actin over myosin.
Match the items given in Column I with those in Column II and select the correct option given below
Column I | Column II | ||
a | Glycosuria | i | Accumulation of uric acid in joints |
b | Gout | ii | Mass of crystallised salts within the kidney |
c | Renal calculi | iii | Inflammation in glomeruli |
d | Glomerular nephritis | iv | Presence of in glucose urine |
a | b | c | d |
iii | ii | iv | i |
a | b | c | d |
i | ii | iii | iv |
a | b | c | d |
iv | i | ii | iii |
a | b | c | d |
ii | iii | i | iv |
C.
a | b | c | d |
iv | i | ii | iii |
Glycosuria denotes presence of glucose in the urine. This is observed when blood glucose level rises above 180 mg/100 ml of blood, this is called renal threshold value for glucose.
Gout is due to deposition of uric acid crystals in the joint. Renal calculi are precipitates of calcium
phosphate produced in the pelvis of the kidney.
Glomerular nephritis is the inflammatory condition of glomerulus characterised by proteinuria and haematuria.
The globular head of myosin contains
Calcium ions in large quantities
Troponin
ATPase enzyme
ATP
C.
ATPase enzyme
Globular head of myosin contains an ATPase enzyme that along with CO2+ and Mg2+ ions catalyses the breakdown of ATP during muscle contraction. It also has a binding site for ATP and active sites for actin.
Sliding filament theory can be best explained as
When myofilaments slide pass each other actin filaments shorten while myosin filament does not shorten
Actin-myosin filaments shorten and slide pass each other
Actin and myosin filaments do not shorten, but rather slide pass each other
When myofilament slide passes each other myosin filament shorten while actin filament do not shorten.
B.
Actin-myosin filaments shorten and slide pass each other
According to sliding filament theory, during muscle contraction actin and myosin filaments shorter and slide pass each other.
Select the correct combination of statements regarding Myasthenia gravis.
I, III, IV,V
I, III,V II
I, II, IV, V
II, III, IV, V
A.
I, III, IV,V
Statements I, II, IV and V are correct. Myasthemia Gravis is an auto immune neuromuscular disease that is congenital. It leads to muscle weakness. It caused by circulating to muscle weakness. It is caused by circulating antibodies that block acetylcholine receptors at the post-synaptic neuromuscular junction inhibiting the excitatory effects of acetylcholine and nicotic receptors at neuromuscular junctions. The first noticeable symptom is weakening of eye muscle leading to drooping of eyelids.
It is treated medically with acetylcholine esterase inhibitors or immuno-suppressants.
What will happen if ligaments are torn?
Bone will become unfixed
Bone will become fixed
Bone less movable at joint and pain
Bone will move freely at joint and no pain
C.
Bone less movable at joint and pain
Ligaments join a bone with another bone in movable/ synovial joints. Torn ligaments make a movement at joints very painful and restricted. It heals only after prolonged movement restriction.
Achondroplasia is a disease related with the defect in the formation of
membrane
mucosa
bone
cartilage
D.
cartilage
Achondroplasia is a defect in the formation of cartilage at the epiphyses of long bones producing a form of dwarfism.
Yellow bone marrow is found specially in the medullary cavity
Long bones
Spongy bones
Short bones
All of the above
A.
Long bones
Bone marrow is of two types; red and yellow. The yellow marrow is found especially in the medullary cavity of long bones, while red is in spongy bones.
Match the items of column I with column II and choose the correct option from the codes given below.
Column I | Column II |
A. Neuron | 1. Ossein |
B. Bone-matrix | 2. Nissl’s bodies |
C. RBCs of man | 3. Antibodies |
D. Lymphocytes | 4. Non-nucleated |
A | B | C | D |
4 | 1 | 2 | 3 |
A | B | C | D |
2 | 1 | 4 | 3 |
A | B | C | D |
3 | 4 | 1 | 2 |
A | B | C | D |
2 | 3 | 4 | 1 |
B.
A | B | C | D |
2 | 1 | 4 | 3 |
Space in the jaw bone unoccupied by teeth is called
Dentine
diastema
enamel
crown
B.
diastema
Diastema is the gap that separates the big teeth from the grinding teeth in herbivores. It creates a space in which food can be held ready for the grinding action of the teeth. This space is filled with large canine teeth in carnivores.
Change in the number of body parts is called
Continuous variation
Discontinuous variation
Meristic variation
Substantive variation
C.
Meristic variation
Meristic variations involve any change in the number of body parts. In other words, it may be defined as the numerical variation in the taxonomic characters, e.g., number of spots, vertebrae, etc.
Which of the following disorder is an outcome of irregularities in the metabolism of the nitrogenous waste?
Osteoporosis
Gouty Arthritis
Osteoarthritis
Rheumatoid arthritis
B.
Gouty Arthritis
Uric acid, a normal waste product of nucleic acid metabolism gets excreted normally through urine. When over concentration in blood, it gets deposited in the form of crystals in joints causing gouty arthritis.
In the following diagram showing axon terminal and synapse A, B, C, D and E respectively represent
A-axon terminal, B-synaptic cleft, C-synaptic vesicles, D-neurotransmitters, E-receptors
A- axon terminal, B-synaptic vesicles, C-synaptic cleft, D-receptors, E-neurotransmitters
A-synaptic cleft, B-synaptic vesicles, C-axon terminal, D-neurotransmitters, E-receptors
A-synaptic vesicles, B-axon terminal, C-synaptic vesicles, D-neurotransmitters, E-receptors
B.
A- axon terminal, B-synaptic vesicles, C-synaptic cleft, D-receptors, E-neurotransmitters
Which of the following tissue is a vascular?
Cowpait bone
Skeletal muscle
Stratified squamous epithelium
Adipose tissue
C.
Stratified squamous epithelium
The stratified squamous epithelial tissue is present on the skin. The outermost larger of this issue is vascular.
The following is the diagram of TS of another. Identify the parts labelled as A, B and C.
A-Connective, B-Endothecium, C-Pollen grain
A-Endothecium, B-Connective, C-Pollen grain
A-Pollen grain, B-Connective, C-Endothecium
A-Endothecium, B-Pollen grain, C-Connective
A.
A-Connective, B-Endothecium, C-Pollen grain
The typical another is tetrasporangiate. It has a column of sterile tissue called connective tissue. Mature another is comprised of an epidermis followed by endothecium, 2 or 3 middle layer and single layered tapetum (innermost).
The largest muscle in the human is
Biceps
Gluteus maximus
Stapedius
Masseter
B.
Gluteus maximus
In human body masseter muscle is the strongest muscle, gluteus maximus is the largest and stapedius is the smallest muscle.
Which one of the following is not correct pair of type of cancer and origin place?
Benign tumour – Non-cancerous tumour
Carcinomas – Cancer of epithelial tissues
Lymphomas – Haematopoietic cells tumour
Sarcomas – Cancer of glands (secretory tissues)
D.
Sarcomas – Cancer of glands (secretory tissues)
Sarcomas cancer originate in lymphatic tissues,connective tissues, muscles and bones.
Epiphyseal plates at the extremities of long bones help in
Bone moulding
Elongation of bone
Bone formation
Formation of Haversian Canal
B.
Elongation of bone
Epiphyseal plate is found between diaphysis and epiphysis. It contributes to the elongation of bone during the growth period.
The strongest muscle in the human is
Biceps
Gluteus maximus
Stapedius
Masseter
D.
Masseter
The masseter is a thick rectangular muscle in the cheek, one of the four muscles of mastication.
The functional unit of the contractile system in striated muscle is
Cross Bridge
Myofibril
Myofibril
Z-band
C.
Myofibril
A skeletal muscle consists of a bundle of long fibres running the length of the muscle. Each fibre is a single cell with many nuclei.
Skeletal muscle is also called striated muscle because of the regular arrangement of the and dark bands. Each repeating pattern of light and dark bands.
Each repeating unit is a sarcomere, the basic functional unit of the muscle. The borders of the sarcomere, the Z-lines are lined up in adjacent myofibrils and contribute to the striations visible with a light microscope. The thin filaments are attached to the Z-lines and project towards the centre of the sarcomere while the thick filaments are centred in the sarcomere. At rest, the thick and thin filaments do not overlap completely, and the area near the edge of the sarcomere where there are only thin filaments is called the I -band.
The A-band is the broad region that corresponds to the length of the thick filaments. The thin filaments do not extend completely across the sarcomere. So, the H-zone in the centre of the A-band contains only thick filaments. This arrangement of thick and thin filaments is the key to how the sarcomere and hence, the whole muscle contracts.
The joint between atlas and axis is called
Pivot joint
Hinge joint
Saddle joints
Angular joint
A.
Pivot joint
Axis vertebra possesses a peg-like structure called the odontoid process which projects forward from the centrum. It fits into the cavity of the atlas below the ligament so that it is separated from the neural canal. Such an arrangement gives a pivot joint which allows the head to shake (rotate from one side to the other).
One animal that does not perform locomotion is
Sycon
Nereis
Sepia
Euglena
A.
Sycon
Sycon (Scypha) is a sponge and does not perform locomotion. It is a genus of calcareous sponges belonging to family-Scyettidae, Class-Calcaronea and phylum-Porifera. These sponges are small, growing upto 5 cm in total length, and are tube shaped and often white to cream in colour.
During strenuous excercise, glucose is converted into
glycogen
pyruvic acid
starch
lactic acid
D.
lactic acid
During strenuous excercise, anaerobic respiration of glucose takes place and Pyruvic acid (a product of glycolysis of glucose) changes into lactic acid. Accumulation of lactic acid is responsible for muscle fatigue. Glycogen is a polysaccharide and stroing material of animal body. It is stored in muscle and liver.
Starch is also a polysaccharide but a storing material of plant body.
Which of the following is important for muscle contraction and nerve impulse transmission?
Ca2+ ions
Ca2+ and Mg2+ ions
Mg2+ ions
Fe2+ ions
B.
Ca2+ and Mg2+ ions
Ion | Important for |
Ca2+ | Muscle contraction and nerve impulse transmission |
Mg2+ | Muscle contraction |
Na2+ | Nerve impulse transmission |
K+ | Nerve impulse transmission and muscle contraction |
Which of the following is a transparent tissue?
Tendon
Fibrous cartilage
Hyaline cartilage
All of these
C.
Hyaline cartilage
Hyaline cartilage is the most abundant kind of cartilage with no fibres and transparent matrix. It is found upon articular surfaces at joints of long bones. It helps to from the nose, larynx, trachea, bronchi and bronchial tubes leading to the lungs.
Fibrocartilage (fibrous cartilage) carries thick dense bundles of white collagen fibres in matrix. They are the strongest cartilage. They occur in joints between vertebrae and also pubic symphysis.
Tendon is a very dense, strong fibruous connective tissue made of collagen fibres. Tendon connects a skeletal muscle to a bone.
In rabbit, end of a long bone is connected in another by
tendon
ligaments
muscle
cartilage
B.
ligaments
Ligaments consist of mainly collagen fibres and some elastic fibres. It connects end of a long bone to another.
Tendon is a very dense, strong fibrous connective tissue made of collagen fibres. It connects a skeletal muscle to a bone.
Cartilage is a solid but semi- rigid and flexible connective tissue. cartilage like the fibrous tissues, is a vascular and nutrients must diffuse into it from nearby tissues.
Muscles are composed of muscle tissue, that contracts to affects a particular movement.
Which of the following is important for muscle contraction and nerve impulse transmission?
Ca2+ ions
Mg2+ ions
Both (a) and (b)
Fe2+ ions
A.
Ca2+ ions
Ca2+ ions are essential for muscle contraction, neutro- muscular functions and nerve impulse transmission. During its transmission, impulse arrives at a synaptic knob, Ca2+ ions diffuse into the knobs from surrounding tissue fluid.
It basically triggers a process in which numerous synaptic vesicles fuse with the membrane of the knob and the areas of fusion break down, releasing the contents of vesicles into the fluid of synaptic clefts.
Spindle fibre is made up of
tubulin
humulin
intermediate filament
flagelin
A.
tubulin
Tubulin is a cytoskeletal globular protein that polymerizes to form microtubules. These radiate from each end of the cell to form a basket like arrangement which helps in the movement of chromosomes to poles. Microtubules also play an important role in the movement of cilia and flagella.
Intermediate filaments are tough rope- like bundles or protein (keratin, desmin, peripherin, vimentin). They provide mechanical stability to cells and interact with microfilaments and microtubules to form cytoskeleton.
Action potential is generated by
Na+
K+
Ca+
Cl-
A.
Na+
Action potential refers to the electrical potential difference across an axon membrane, that is stimulated (action). Action potential is generated by Na+.
It occurs when the membrane potential of a specific axon location rapidly rises and falls. And this depolarisation leads to the adjacent locations to similary depolarize.
Ligament is mainly made up of
reticulin
elastin
myosin
collagen
D.
collagen
Ligament is a tough cord or fibrous band of dense regular connective tissue that contains numerous parallel arrangements of collagen fibres. It connects bones or cartilages and serves to strengthen joints.
Sigmoid notch is formed by
cavity formed by humerus
cavity formed by radius-ulna
cavity formed by tibia-fibula
cavity formed by femur
B.
cavity formed by radius-ulna
Radius and ulna are the bones of the forearm which are closely held together. The ulna is the long bone and bears a deep sigmoid notch for articulation with the trochlea of the humerus.
An acromian process is characteristically found in the
pelvic girdle of mammals
skull of frog
pectoral girdle of mammals
sperm of mammals
C.
pectoral girdle of mammals
Acromion process is a bony process on the scapula. Scapula is a large triangular flat bone situated in the dorsal part of the thorax between the second and seventh ribs.
The acromion is a continuation of the scapular spine, and hooks over anteriorly. It articulates with the clavicle to form the acromioclavicular joint.
Which of the following pairs is correctly matched?
Cartilaginous joint - Skull bones
Hinge joint - Between vertebrae
Fibrous joint - Between phalanges
Gliding joint - Between zygapophyses of the successive vertebrae
D.
Gliding joint - Between zygapophyses of the successive vertebrae
Gliding joint is present between zygapophyses of the successive vertebrae.
The thin filaments of a muscle fibre are made up of
actin, troponin, tropomyosin
actin, troponin
myosin, troponin
actin, tropomyosin
A.
actin, troponin, tropomyosin
The thin filaments of a muscle fibre are made up of actin, troponin and tropomyosin. One thin filament probably contains 300-400 actin molecules, about 50 tropomyosin and 50 troponin. It is said that tropomyosin plays a vital role in sensitizing the contractile proteins (actin and myosin) to calcium ions.
Which of the following is a transparent tissue
Tendon
Hyaline cartilage
Fibrous cartilage
All of these
B.
Hyaline cartilage
Hyaline cartilage has a clear, homogenous, transparent bluish-green matrix. It gives glass like appearance. A few bundles of small white fibres are imbedded in the matrix. It is present in the end of limb bones (called hyaline caps).
Total number of bones in the hind limb of a man is
21
23
27
30
D.
30
Hind limb of man consists of 30 bones which are as follows:
An example of stretch reflex triggered by passive muscle movement is the
tendon reflex
ipsilateral reflex
flexor reflex
patellar reflex
D.
patellar reflex
A stretch reflex is the contraction of a muscle in response to a passive stretching of a muscle spindle within a muscle. This reflex enables the body to correct any unintended changes in body posture in a timely manner without waiting for input from the cerebral cortex as well as keeps appropriate tone in muscles. A well known example of stretch reflex is patellar reflex or knee jerk reflex, i.e., sudden kicking movement of the lower leg in response to a sharp tap on patellar tendon.
Achondroplasia is a disease related with the defect in the formation of
membrane
cartilage
mucosa
none of these
B.
cartilage
Achondroplasia is a disorder inherited as dominant characteristic in which bones of arms and legs fail to grow to normal size due to defect in both cartilage and bone. It results in a type of dwarfism characterised by short limbs, a normal sized head and body and normal intelligence.
Assertion: On stimulation, a muscle cell releases calcium ions (Ca2+) from sarcoplasmic
reticulum.
Reason: By reacting with a protein complex, Ca2+ uncover active sites on the actin filaments
If both assertion and reason are true and reason is the correct explanation of assertion.
If both assertion and reason are true but reason is not the correct explanation of assertion.
If assertion is true but reason is false.
If both assertion and reason are false.
B.
If both assertion and reason are true but reason is not the correct explanation of assertion.
A neural signal reaching this junction releases a neurotransmitter (Acetyl choline) which generates an action potential in the sarcolemma. This spreads through the muscle fibre and causes the release of calcium ions into the sarcoplasm. Increase in Ca2+ level leads to the binding of calcium with a subunit of troponin on actin filaments and thereby remove the masking of active sites for myosin.
Which one of the following is not a mammalian character?
Presence of milk producing glands
Skin is unique in possessing hair
Presence of external ears called pinnae
Homodont type of dentition
D.
Homodont type of dentition
Mammals have heterodont type of dentition i.e, teeth are of different types.
The H-zone in the skeletal muscle fibre is due to
the central gap between actin filaments extending through myosin filaments in the A-band
extension of myosin filaments in the central portion ofthe A-band
the absence of myofibrils in the central portion of A-band
the central gap between myosin filaments in the A-band.
A.
the central gap between actin filaments extending through myosin filaments in the A-band
Each muscle fibre has many parallely arranged myofibrils. Each myofibril contains many serially arranged units called sarcomere which are the functiorial units. Each sarcomere has a central 'A' band made of thick myosin filaments, and two half 'T' bands made of thin actin filaments on either side of it marked by Z' lines. In a resting state, the edges of thin filaments on either side of the thick filaments partially overlap the free ends of the thick filaments leaving the central part of the thick filaments. This central part of thick filament, not overlapped by thin filaments is called the 'H' zone.
Select the correct option regarding A, B and C.
A-Tropomyosin-runs close to F-actin throughout its length
B-Troponin-complex protein distributed at regular interval of tropomyosin
C-F actin-polymer of monomeric G-actin helically bound to each other
None of these
C.
C-F actin-polymer of monomeric G-actin helically bound to each other
A - Troponin
B - Tropomyosin
C - F-actin
Two filaments of protein tropomyosin run close to F-actins throughout its length. A complex protein troponin is distributed at regular intervals on the tropomyosin. In the resting state, a subunit of troponin masks the active binding sites for myosin on the actin filaments.
Assertion: In a pivot joint, rounded or pointed bone fits into a shallow depression in another bone.
Reason: Pivot joints are present between the metacarpals and phalanges of the fingers.
If both assertion and reason are true and reason is the correct explanation of assertion.
If both assertion and reason are true but reason is not the correct explanation of assertion.
If assertion is true but reason is false.
If both assertion and reason are false.
C.
If assertion is true but reason is false.
The joints between the atlas and axis and between the radius and ulna just below the elbow are the examples of pivot joints.
What is diapedesis?
A kind of amoeboid movement.
The process of filtration of urea in kidney.
A type of locomotion found in Hydra
Migration of WBCs into the tissue spaces from blood capillaries
D.
Migration of WBCs into the tissue spaces from blood capillaries
WBCs can change their shape like amoeba and are thus, capable of amoeboid movement. This enables them to squeeze out of blood capillaries into the tissues. This process is called diapedesis.
Which one of the following is a sesamoid bone?
Pelvis
Patella
Pterygoid
Pectoral girdle
B.
Patella
Patella is a sesamoid bone. Sesamoid bones are small rounded masses of bones formed in tendons at the joints where they are subjected to great pressure.
The shoulder blade is made of
clavicle
humerus
ilium
scapula
D.
scapula
Scapula (shoulder blade) is the largest of the bones that make up each half of the pectoral (shoulder) girdle. It is a flat triangular bone, providing anchorage for the muscles of the forelimb and an articulation for the humerus at the glenoid cavity. It is joined to the clavicle (collar bone) in front.
Clavicle is a bone that forms part of the pectoral (shoulder) girdle, linking the scapula (shoulder blade) to the sternum (breast bone). In humans it forms the collar bone and serves as a brace for the shoulders.
Humerus is the long bone of the upper arm which articulates with the scapula (shoulder blade) at the glenoid cavity and with the ulna and radius (via a condyle) at the elbow.
Ilium is the largest of the three bones that make up each half of the pelvic girdle. The ilium bears a flattened wing of bone that is attached by ligaments to the sacrum.
A cricket player is fast chasing a ball in the field. Which one of the following groups of bones are directly contributing in this movement
Femur, malleus, tibia, metatarsals
Pelvis, ulna, patella, tarsals
Sternum, femur, tibia, fibula
Tarsals, femur, metatarsals, tibia
D.
Tarsals, femur, metatarsals, tibia
Tarsal- Tarsal, any of several short, angular bones that in humans make up the ankle and that—in animals that walk on their toes (e.g., dogs, cats) or on hoofs—are contained in the hock, lifted off the ground. The tarsals correspond to the carpal bones of the upper limb.
Femur- Femur, also called thighbone, or hind leg. The head forms a ball and socket with the hip (at the acetabulum), being held in place by a ligament (ligamentum teres femoris) within the socket and by strong surrounding ligaments.
Metatarsals- Anatomical terms of bone. The metatarsal bones, or metatarsus are a group of five long bones in the foot, located between the tarsal bones of the hind- and mid-foot and the phalanges of the toes
Tibia- The tibia, also known as the shinbone or shankbone, is the larger, stronger, and anterior (frontal) of the two bones in the leg below the knee in vertiberates (the other being the fibula, behind and to the outside of the tibia), and it connects the knee with the ankle bones.
Given diagram shows bone of the left human hindlimb as seen from front. It has certain mistakes in labeling. Two of the wrongly labelled bones are
tibia and tarsals
femur and fibula
fibula and phalanges
tarsals and femur
C.
fibula and phalanges
In the above figure, two parts of hindlimb that are wrongly marked are fibula and phalanges.
Assertion: Eukaryotic cells have the ability to adopt a variety of shapes and carry out directed movements.
Reason: There are three principal types of protein filaments - microfilaments, microtubules and intermediate filaments, which constitute the cytoskeleton.
If both assertion and reason are true and reason is the correct explanation of assertion.
If both assertion and reason are true but reason is not the correct explanation of assertion.
If assertion is true but reason is false.
If both assertion and reason are false.
A.
If both assertion and reason are true and reason is the correct explanation of assertion.
The cytoskeleton is a fibrous network made or proteins that contributes to the structure and internal organization of eukaryotic cells within the cytoplasm. It is a dynamic structure that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (the movement of vesicles and organelles, for example) and cellular division.
The cytoskeleton has three major fibre types: microfilaments made ofactin protein, intermediate filaments made or various kinds of proteins (eg keratin), and microtubules made of tubulin.
Which one of the following is a sesamoid bone?
Pelvis
Patella
Pterygoid
Pectoral girdle
B.
Patella
Patella is a sesamoid bone. Sesamoid bones are formed by ossification of a tendon where the tendon moves over a bony surface.
During muscle contraction
size of 'A' bands remain same
size of 'H' zone becomes smaller
size of 'I' band decreases
diameter of fibre increases
A.
size of 'A' bands remain same
During muscle contraction, both I-band and H-zone progressively shorten and eventually disappear while length of A-band remains constant.
The main difference between white and yellow fibres is of
protein
colour of fibres
both (a) and (b)
none of the above
A.
protein
White fibre is made. up of collagen protein whereas yellow fibre is made up of elastin protein.
Metha Jahar which is useful in rheumatism is obtained from
Aconitum napellus
Colchicum
Exogonium
Licorice
A.
Aconitum napellus
Metha Jahar drug is commonly known as aconite. It obtained from the roots of Aconitum napellus. It is used externally for rheumatism and internally to relieve pain and fever.
Ball and socket joints can be seen in
wrist
fingers
neck
shoulders
D.
shoulders
Ball-and-socket joint, also called spheroidal joint, in vertebrate anatomy, a joint in which the rounded surface of a bone moves within a depression on another bone, allowing greater freedom of movement than any other kind of joint.
Ball and socket joints are found in shoulder joint (humerus in glenoid cavity) and hip joint (femur in acetabulum).
Which ribs show 'bucket-handle' type of movement?
Rib no. 1-2
Rib no. 3-5
Rib no. 6-10
Rib no. 11-12
C.
Rib no. 6-10
The intermediate ribs 6 and 7 show both pump handle and bucket handle types of movement. Movement of ribs eight to ten results in an outward and upward movement of their anterior ends.
State two differences between red and white muscles.
Red Muscles | White Muscles |
Have more mitochondria | Have less mitochondria |
Presence of myoglobin. | Absence of myoglobin. |
Have slow rate of contraction. | Have fast rate of contraction. |
Osteomalacia is a disease caused by the deficiency of
calciferol
tocopherol
retinol
phylloquinone
A.
calciferol
Osteomalacia means soft bones. Bone is a living, active tissue that’s continually being removed and replaced. This process is known as bone turnover. Bone consists of a hard outer shell (the cortex) made up of minerals, mainly calcium and phosphorus, and a softer inner mesh (the matrix) made up of collagen fibres.
Collagen is a
phosphoprotein
globulin
derived protein
scleroprotein
D.
scleroprotein
Scleroproteins or fibrous proteins constitute one of the three main types of proteins. There are many scleroprotein superfamilies including keratin, collagen, elastin, and fibroin. The roles of such proteins include protection and support, forming connective tissue, tendons, bone matrices, and muscle fiber.
The generation of excitation-contraction coupling involves all the following events except
generation of end-plate potential
release of calcium from troponin
formation of cross-linkages between actin and myosin
hydrolysis of ATP to ADP
B.
release of calcium from troponin
When the depolarization spreads along the sarcolemma and down the T tubules, creating an action potential. The action potential triggers the sarcoplasmic reticulum to release of Ca2+, which activate troponin and stimulate muscle contraction.
Spindle fibre is made up of
humulin
intermediate filament
flagellin
tubulin
D.
tubulin
The spindle microtubules are protein fibers made up of as many as 45 different proteins, primarily of alpha and beta tubulin, that grow from the centrioles. They form a polymer, which is a large molecule made up of many similar molecules linked together.
Osteomalacia is a deficiency disease of
infants due to protein energy malnutrition
adults due to protein energy malnutrition
adults due to vitamin-D deficiency
infants due to vitamin-K deficiency
C.
adults due to vitamin-D deficiency
Deficiency of vitamin-Dcauses weak bones, bone deformitis, rickets in children and osteomalacia in adults.
Marasmus is caused due to protein energy malnutrition.
Cardiac muscles are
striated and voluntary
striated and involuntary
smooth and voluntary
smooth and involuntary
B.
striated and involuntary
Cardiac muscles are predominantly found in heart wall. These are striated, involuntary contract quickly and do not get fatigued. These, muscles continue rhythmic contraction throughout life under the control of ANS.
All or none law is not applicable for
whole skeletal muscle
single skeletal muscle fibre
whole cardiac muscle
single smooth muscle fibre
A.
whole skeletal muscle
All or none law or Bowditch's law is a principle which states that response of a muscle nerve to a stimulus is not proportionate to the intensity of stimulus but is either present in full strength or completely absent. This law is applicable to single muscle fibre but entire muscle does not follow this law.
Bone is mainly composed of
iron and phosphorus
sulphur and calcium
calcium and phosphorus
calcium and magnesium
C.
calcium and phosphorus
The matrix of bone has 60-70% mineral salts like calcium phosphate (main component), calcium carbonate, magnesium phosphate, chloride and fluoride. 30-40% of matrix is organic matter, chiefly protein ossein.
The H-zone in the skeletal muscle fibre is due to
the absence of myofibrils in the central portion of A-band
the central gap between myosin filaments in the A-band
the central gap between actin filaments extending through myosin filaments in the A-band
extension of myosin filaments in the central portion of the A-band
C.
the central gap between actin filaments extending through myosin filaments in the A-band
H-zone in skeletal muscle is the central gap between actin filaments extending through myosin filaments in the A-band. Alternate arrangement of dark and light bands gives the striated appearance to a skeletal muscle. At the centre of A-band, a comparatively less dark zone called H-zone is present. In the centre of H-zone, M-line is present, formed by the threats that connect the myofilaments.
Select the correct statement with respect to locomotion in humans
A decreased level of progesterone causes osteoporosis in old people
Accumulation of uric acid crystals in joints causes their inflammation
The vertebral column has 10 thoracic vertebrae
The joint between adjacent vertebrae is a fibrous joint
B.
Accumulation of uric acid crystals in joints causes their inflammation
Inflammation of joints due to accumulation of uric acid crystals is gout. Fibrous joint are formed by the flat skull bones, which fuse end-to-end with the help of dense fibrous connective tissues in the form of sutures to form cranium. The vertebral column is formed by 26 serially arranged units called vertebral. The less secretion of progesterone causes aportion as it basically supports pregnancy.
The characteristics and an example of a synovial joint in humans is
Characteristics | Examples |
Fluid cartilage between two bones, limited movements | Knee joints |
Fluid filled between two joints, provides cushion | Skull bones |
Fluid filled synovial cavity between two bones | Joint between atlas and axis |
Lymph filled between two bones, limited movement | Gliding joint between carpals |
C.
Fluid filled synovial cavity between two bones | Joint between atlas and axis |
Joint between atlas and axis is pivot joint, which is an example of synovial joint characterised by the presence of a fluid-filled synovial cavity between the articulating surface of the two bones.
Knee joint (hinge joint) is a synovial joint characterised by the presence of fluid filled synovial cavity between the articulating surfaces of the two bones.
Fluid cartilage between two bones having limited movements is slightly movable joint. In freely movable joints fluid filled between two joints provides cushion.
In gliding joint, the articulating bones can slide upon one another.
The disease that occurs in mature adult human being due to deficiency of calciferol is
keratomalacia
osteomalacia
glossitis
pernicious anaemia
B.
osteomalacia
Calciferol is vitamin-D responsible for enhancing intestinal absorption of calcium, iron, magnesium, phosphate and zinc. It is obtained from diet or from sun exposure. Its deficiency may cause osteomalacia in adults, in which bones of a person becomes soft, weak and fragile. Osteomalacia in children is known as rickets.
Keratomalacia is an eye disorder that results from Vitamin A deficiency.
Glossitis is the inflammation of the tongue.
Pernicious anemia refers to anemia that results from lack of intrinsic factor. It is common due to an autoimmune attack on the cells that create it in the stomach.
Which of the following is not involved in muscular contraction?
Calcium ion
Troponin
Actin
Magnesium ion
D.
Magnesium ion
Muscle contraction is the shortening or tensing of a part or organ (i.e., a muscle fibre). Magnesium ion is not involved directly in the process of muscle contraction.
Actin and troponin are the globular proteins made up of two and three globular peptides respectively. Calcium ion also play a key regulatory role in muscle contraction, i.e., increase in the calcium ion levels lead to their binding to the troponin subunit.
What type of cartilaginous tissue is found in the inter-vertebral discs?
Costal cartilage
Hyaline cartilage
White fibrous cartilage
Yellow elastic cartilage
C.
White fibrous cartilage
White fibrous cartilage is a type of special connective tissue which has little matrix and abundant white collagen fibre. It lacks perichondrium (layers of dense irregular connective tissue that surrounds cartilage of developing bone). It is found in the intervertebral discs where it acts as cushions.
Osteoid refers to
the smallest bone of the body
young hyaline matrix of true bone in which calcium salts are deposited
membranous ossification of cranium
the largest bone of the body
B.
young hyaline matrix of true bone in which calcium salts are deposited
Osteoid refers to the unmineralised organic portion of the bone matrix that forms prior to the maturation of bone tissue. It is a young hyaline matrix of true bone in which calcium salts are deposited. Osteoid makes up about 50% of bone volume and 40% of bone weight.
Read the following statements.
Statement I. The flat bones of skull are spongy without marrow cavity.
Statement II. Specialised Bones of skull in mammals are called diploic bones.
Identify wheather the given statements are true or false and choose the correct option.
Statement I | Statement II |
True | False |
False | True |
True | True |
False | False |
C.
True | True |
The flat bones of skull are specialised as they have spongy bone without marrow cavity. These are covered up by a sheet of compact bone on its both the surface. These specialised bones of skull in mammals are called diploic bones.
Choose the correctly paired sets from the following.
Set I | Set II | Set III |
I. Sphenoid bone | Key- stone bone | Cranium |
II. Acromion process | Collor bone | Scapula |
III. Xiphoid process | Breast bone | Thorax |
IV. Odontoid process | Atlas | Cervical vertebra |
I, IV
II, IV
II, III
I, III
D.
I, III
Set I | Set II | Set III |
I. Sphenoid bone | Key- stone bone | Cranium |
II. Acromion process | Shoulder joint | Scapula |
III. Xiphoid process | Breast bone | Thorax |
IV. Odontoid process | Axis | Second cervical vertebra |
Microtubules are assembled from molecules of the protein tubulin, which is a
monomer
dimer
trimer
pentamer
B.
dimer
Microtubules are assembled from tubulin protein, which is a dimer, made up of two monomers namely -tubulin and -tubulin.
Study the following and identify the incorrect statements.
I. Muscles of the iris end ciliary body are the smooth muscles of mesodermal origin.
II. Slow and sustained involuntary contractions of smooth muscles are called spasms.
III. Quiescent mononucleate myogenic cells of skeletal muscles are called pericytes.
IV. The skeletal muscle fibre is multinucleate and is a synctium.
I, IV
II, IV
III, IV
I, III
D.
I, III
Statement I, II and III are incorrect. But this is not given in the options. The above statements can be corrected as follows:
(I) Muscles of the iris and ciliary body are ectodermal in origin.
(II) A sudden involuntary contraction of muscles is called spasm. Slow, involuntary and sustained muscles contraction of hand, toes and feet is called dystonia.
(III) Pericytes are contractile cells surrounding endothelial cells of capillaries also known as mural cells or rouget cells.
Match the following Columns
Column I | Column II |
A. Pisiform bone | i. Ruminants |
B. Fibrous cartilage | ii. Wrist bone |
C. Hyaline cartilage | iii. Intervertebral discs |
D. OS- cardis |
iv. Larynx v. Pinna |
The correct answer is
A - ii; B - iii; C - iv; D - v
A - v; B - ii; C - i; D - iv
A - iv; B - iii; C - ii; D - i
A - v; B - ii; C - iii; D - iv
A.
A - ii; B - iii; C - iv; D - v
Column I | Column II |
A. Pisiform bone | ii. Wrist bone |
B. Fibrous cartilage | iii. Intervetrebral discs |
C. Hyaline cartilage | iv. Larynx |
D. OS- cardis | i. Ruminants |
Thousand of years old mummies are still in their condition as they were before due to some reason. Which of the following describe it the best?
Due to non-destruction of yellow elastin fibre
Due to non-destruction of white elastin fibre
Due to non-destruction of collagen fibre
Due to non-destruction of veins
A.
Due to non-destruction of yellow elastin fibre
The thousand year old mummies have their arteries intact due to well preserved yellow elastic fibres, which is present in the walls of blood vessels, lungs, bronochioles, etc. These elastic connective tissue fibres have considerable strength and remarkable elasticity.
Patella (knee cap) is an example of
replacing bones
sesamoid bones
flat bones
irregular bones
B.
sesamoid bones
Sesamoid bones are small rounded masses of bones formed in tendons at the joints, where they are subjected to great pressure. e.g., patella, fabellae.
Caudal vertebrae of man are united to form a single
synsacrum
pygostyle
coccyx
None of these
C.
coccyx
The bones of the tail, which articulate with the sacral vertebrae. The number of caudal vertebrae varies with the species. The coccyx is a triangular arrangement of bone that makes up the very bottom portion of the spine below the sacrum. It represents a vestigial tail, hence the common term tailbone.
Synsacrum and pygostyle are unique features of aves.
All the following are the properties of skeletal muscles except
excitability
contractility
rhythmicity
toxicity
C.
rhythmicity
Excitability, contractibility and toxicity are the properties of skeletal muscles. Rhythmicity is one of the property or feature of cardiac balance.
Which of the following is a part of pectoral girdle?
Ilium
Ischium
Acetabulum
Glenoid cavity
D.
Glenoid cavity
Pectoral girdle or shoulder girdle is composed of two separate halves. Each half consists of the scapula or shoulder bone, coracoid process and clavicle or collar bone. At the junction of scapula and clavicle, is a concave depression, called glenoid cavity, which articulates with the head of the humerus to form a ball and socket joint.
Which of the following type of cartilage is found in intervertebral disc of mammal?
Hyaline cartilage
Fibrous cartilage
Calcified cartilage
Elastic cartilage
B.
Fibrous cartilage
White fibrous cartilage contains more collagen fibres and lack perichondrium. It is the strongest cartilage in vertebrate body and is required where great tensile strength, flexibility and rigidity is needed. It is found in intervertebral disks and pubic symphysis of pelvic girdle.
The sliding filament theory of muscle contraction was proposed by
A.F. Huxley and A.P. Pullman
A.F. Huxley and H.E. Huxley
B. Pullman and A.F. Huxley
A. Pullman and E. Pullman
B.
A.F. Huxley and H.E. Huxley
A.F. Huxley and H.E. Huxley elucidated the mechanism of contraction and relaxation of straited muscle fibres. They proposed that the shortening of fibrils in contraction is brought about by sliding movement of actin filaments over myosin filaments.
Achilles tendon is associated with :
gluteus muscle
hamstring muscle
quadriceps muscle
gastrocnemius muscle
D.
gastrocnemius muscle
Achilles tendon is the strongest and thickest tendon in the body. It is a tough band of fibrous tissue that connects the calf muscles to the heel bone (calcaneus). Former is a large tendon atlower end of the gastrocnemius muscle, inserted into oscalcis.
Sponsor Area
Sponsor Area