Human Health and Disease

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Question
CBSEENBI12002456

A certain patient is suspected to be suffering from Acquired Immuno Deficiency Syndrome. Which diagnostic technique will you recommend for its detection?

  • MRI

  • Ultra Sound

  • WIDAL

  • ELISA

Solution

D.

ELISA

ELISA (Enzyme-linked Immunosorbent Assay), also known as an enzyme immunoassay (EIA), is a biochemical technique used mainly in immunology to detect the presence of an antibody or an antigen in a sample. It is a useful tool for determining serum antibody concentrations (such as with the HIV test). The ELISA was the first screening test widely used for HIV because of its high sensitivity.

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Question
CBSEENBI12002610

A health disorder that results from the deficiency of thyroxin in adults and characterised by
(i) a low metabolic rate
(ii) increase in body weight
(iii) tendency to retain water in tissue is 

  • hypthyroidism

  • simple goitre

  • myxoedema

  • cretinism

Solution

C.

myxoedema

Myxoedema (Gulls disease) occurs due to the deficiency of thyroxine in adults, it causes low BMR (by 30-40%), low body temperature, tendency to retain water in tissue, reduced heart rate, pulse rate, blood pressure and cardiac output, low sugar and iodine level in  blood, muscular weakness and oedema (accumulation of interstitial fluid that causes the facial tissues to swell and look fluffy).

Question
CBSEENBI12002779

A person showing unpredictable moods, outbursts of emotion, quarrelsome behaviour and conflicts with others is suffering from

  • schizophrenia

  • borderline personality disorder (BPD)

  • mood disorders

  • addictive disorders

Solution

A.

schizophrenia

Schizophrenia is any of a group of severe mental disorders that have in common, symptoms as hallucinations, delusions, blunted emotions, disordered thinking and a withdrawl from reality.

Question
CBSEENBI12002602

A person suffering from a disease caused by Plasmodium experiences recurring chill and fever at the time when the

  • sporozoites released from RBCs are being rapidly killed and broken down inside spleen

  • trophozoites reach maximum growth and give out certain toxins

  • Parasite after its rapid multiplication inside RBCs ruptures them, releasing the stage to enter fresh RBCs

  • microgametcytes and megagametocytes are being destroyed by the wBCs

Solution

C.

Parasite after its rapid multiplication inside RBCs ruptures them, releasing the stage to enter fresh RBCs

In malaria, chill and fever are due to the release of a toxic substance haemozoin, formed by the breakdown of haemoglobin present in RBCs. It will be released after the rupture of RBCs in erythrocytic schizogony.

Question
CBSEENBI12002665

A transgenic food crop, which may help in solving the problem of night blindness in developing countries is

  • Flavr savr tomatoes

  • Starlink maize

  • Bt soybean

  • Golden rice

Solution

D.

Golden rice

Vitamin -A deficiency causes night blindness among children. Vitamin - A deficiency often occurs where rice is the staple food since rice grain does not contain Beta carotene. Three transgenic providing phytoene synthase, phytoene desaturase, zeta-carotene desaturase and lycopene cyclase activities were transferred into rice by Agrobacterium mediated transformation. The resulting transgenic rice popularly called golden rice contains good quantities of Beta-carotene.
Flavr savr is genetically modified tomato, which remains fresh and retains their flavour much longer than normal tomato due to blocking of synthesis of fruit softening enzyme polygalacturonase.

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